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QuickView for RC3H1;jsessionid=3330AAACC1084E8D3675E281A0323905;jsessionid=D98C390DA2135E67BEB17A391B946363 (gene)


Gene Symbol:
Rc3h1 Mus musculus Mus musculus
Full name:
RING CCCH (C3H) domains 1
Synonyms:
5730557L09Rik, Gm551, N28103, mKIAA2025, roquin-1, RING finger and C3H zinc finger protein 1, RING finger and CCCH-type zinc finger domain-containing protein 1, probable E3 ubiquitin-protein ligase Roquin, protein Sanroque, roquin
Genomic Location:
Chr 1: 162836601-162897985
Orthologs:
Homo sapiens Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_001024952
XM_006496908
Protein Names
Q4VGL6
B2RS13
Q69Z31



GO Molecular Function

RNA stem-loop binding | cation binding | nucleic acid binding | mRNA binding | catalytic activity | ubiquitin-like protein transferase activity | miRNA binding | ion binding | organic cyclic compound binding | protein binding | zinc ion binding | ubiquitin-protein transferase activity | transferase activity | transition metal ion binding | mRNA 3'-UTR binding | metal ion binding | heterocyclic compound binding | RNA binding | double-stranded RNA binding

GO Biological Process

positive regulation of immune response | negative regulation of lymphocyte differentiation | RNA metabolic process | leukocyte homeostasis | negative regulation of leukocyte activation | negative regulation of immune system process | CD4-positive, alpha-beta T cell differentiation | response to cytokine | response to interleukin-1 | regulation of B cell activation | CD4-positive, alpha-beta T cell activation | negative regulation of activated T cell proliferation | immune response-regulating signaling pathway | immune response-regulating cell surface receptor signaling pathway | regulation of immune system process | regulation of T-helper 17 type immune response | negative regulation of cellular process | negative regulation of leukocyte cell-cell adhesion | cell differentiation | immune response-activating cell surface receptor signaling pathway | regulation of T cell differentiation | T cell receptor signaling pathway | negative regulation of B cell proliferation | cellular process | organic substance catabolic process | lymphocyte differentiation | negative regulation of germinal center formation | immune system development | negative regulation of alpha-beta T cell differentiation | negative regulation of T-helper 17 cell differentiation | positive regulation of nitrogen compound metabolic process | negative regulation of T cell proliferation | negative regulation of cellular metabolic process | regulation of T cell receptor signaling pathway | regulation of cell differentiation | negative regulation of CD4-positive, alpha-beta T cell activation | positive regulation of mRNA catabolic process | regulation of mRNA stability | regulation of immune response | regulation of cellular process | leukocyte activation | regulation of metabolic process | catabolic process | T cell differentiation involved in immune response | negative regulation of mononuclear cell proliferation | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | mRNA catabolic process | T cell activation | response to stimulus | positive regulation of NIK/NF-kappaB signaling | alpha-beta T cell activation involved in immune response | positive regulation of immune system process | negative regulation of cell adhesion | regulation of CD4-positive, alpha-beta T cell activation | mononuclear cell proliferation | negative regulation of lymphocyte activation | leukocyte activation involved in immune response | posttranscriptional regulation of gene expression | regulation of cell proliferation | cellular nitrogen compound metabolic process | immune response-activating signal transduction | negative regulation of metabolic process | hemopoiesis | cellular component assembly | negative regulation of hemopoiesis | protein modification process | mRNA metabolic process | nuclear-transcribed mRNA catabolic process | regulation of cell adhesion | macromolecule modification | nucleobase-containing compound catabolic process | regulation of lymphocyte differentiation | negative regulation of adaptive immune response | T-helper cell differentiation | leukocyte differentiation | organelle assembly | system development | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of T-helper cell differentiation | 3'-UTR-mediated mRNA destabilization | multicellular organism development | spleen development | regulation of CD4-positive, alpha-beta T cell differentiation | regulation of miRNA metabolic process | regulation of T cell activation | regulation of activated T cell proliferation | regulation of gene expression | negative regulation of T-helper 17 type immune response | RNA catabolic process | positive regulation of cellular metabolic process | regulation of lymphocyte activation | regulation of germinal center formation | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | negative regulation of T cell activation | positive regulation of intracellular signal transduction | regulation of RNA stability | alpha-beta T cell differentiation | regulation of T-helper 17 cell differentiation | B cell homeostasis | homeostasis of number of cells | cellular response to cytokine stimulus | cell proliferation | leukocyte proliferation | regulation of cellular protein metabolic process | negative regulation of immune response | T cell activation involved in immune response | cellular protein-containing complex assembly | negative regulation of cell-cell adhesion | mRNA destabilization | cell communication | regulation of cellular metabolic process | regulation of alpha-beta T cell differentiation | lymphocyte homeostasis | negative regulation of cell activation | cell activation involved in immune response | regulation of NIK/NF-kappaB signaling | regulation of protein metabolic process | positive regulation of signal transduction | aromatic compound catabolic process | homeostatic process | negative regulation of CD4-positive, alpha-beta T cell differentiation | regulation of RNA metabolic process | negative regulation of T cell differentiation | negative regulation of B cell activation | lymphocyte activation | protein polyubiquitination | lymph node development | T cell differentiation | protein-containing complex assembly | activation of immune response | protein metabolic process | response to organic substance | protein ubiquitination | regulation of hemopoiesis | regulation of intracellular signal transduction | cellular macromolecule catabolic process | anatomical structure development | cell surface receptor signaling pathway | metabolic process | ubiquitin-protein transferase activity | regulation of adaptive immune response | negative regulation of leukocyte proliferation | immune response | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | regulation of mRNA catabolic process | negative regulation of cellular protein metabolic process | T cell proliferation | regulation of cell activation | ribonucleoprotein complex assembly | alpha-beta T cell activation | protein modification by small protein conjugation or removal | RNA destabilization | cytoplasmic mRNA processing body assembly | antigen receptor-mediated signaling pathway | negative regulation of translation | T cell homeostasis | cell activation | regulation of T-helper cell differentiation | negative regulation of protein metabolic process | lymphocyte proliferation | regulation of cell communication | signaling | regulation of T cell proliferation | cellular protein metabolic process | T follicular helper cell differentiation | regulation of developmental process | developmental process | organelle organization | cellular response to interleukin-1 | cellular protein modification process | negative regulation of alpha-beta T cell activation | regulation of B cell proliferation | negative regulation of cell proliferation | regulation of cell-cell adhesion | heterocycle metabolic process | positive regulation of metabolic process | ribonucleoprotein complex biogenesis | negative regulation of lymphocyte proliferation | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | cellular response to organic substance | regulation of translation | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | negative regulation of cell differentiation | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

cytoplasmic stress granule | cell | ribonucleoprotein granule | cytoplasm | intracellular organelle | P-body | protein-containing complex | ribonucleoprotein complex | organelle | cytoplasmic ribonucleoprotein granule | intracellular