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QuickView for Snai2;jsessionid=6D167CB5A3E9C468F5115DE34FA20F0F;jsessionid=52EB1FA9B21D16165E8660875645E578 (gene)


Gene Symbol:
Snai2 Mus musculus Mus musculus
Full name:
snail family zinc finger 2
Synonyms:
Slug, Slugh, Snail2, zinc finger protein SNAI2, neural crest transcription factor Slug, protein snail homolog 2, slug, chicken homolog, snail homolog 2
Genomic Location:
Chr 16: 14705952-14709478
Orthologs:
Homo sapiens Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio Bos taurus
External Links:
Entrez Gene


Transcripts Names
NM_011415
Protein Names
O09096
P97469
Q9R211
Q3UZ96



GO Molecular Function

sequence-specific DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | cation binding | nucleic acid binding | chromatin binding | DNA binding | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | ion binding | organic cyclic compound binding | protein binding | DNA-binding transcription factor activity | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | metal ion binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | Notch signaling pathway | response to radiation | regulation of extrinsic apoptotic signaling pathway in absence of ligand | positive regulation of locomotion | positive regulation of cellular component organization | cell motility | cellular response to platelet-derived growth factor stimulus | regulation of localization | morphogenesis of an epithelium | negative regulation of vitamin D biosynthetic process | regulation of programmed cell death | cell migration involved in endocardial cushion formation | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | positive regulation of developmental process | negative regulation of RNA biosynthetic process | cell differentiation | positive regulation of endothelial cell chemotaxis | regulation of vitamin metabolic process | epithelial to mesenchymal transition | epithelial to mesenchymal transition involved in endocardial cushion formation | regulation of organelle organization | positive regulation of cellular component movement | mesenchyme development | sensory perception of mechanical stimulus | cellular process | regulation of cell motility | localization | regulation of DNA damage response, signal transduction by p53 class mediator | heart morphogenesis | negative regulation of signaling | regulation of branching involved in salivary gland morphogenesis | canonical Wnt signaling pathway | negative regulation of anoikis | negative regulation of nucleic acid-templated transcription | regulation of histone modification | regulation of chemotaxis | negative regulation of apoptotic process | negative regulation of lipid biosynthetic process | response to growth factor | positive regulation of nitrogen compound metabolic process | regulation of canonical Wnt signaling pathway | negative regulation of keratinocyte proliferation | negative regulation of cellular metabolic process | tissue development | regulation of fat cell differentiation | regulation of cell differentiation | negative regulation of apoptotic signaling pathway | regulation of cellular process | regulation of osteoblast differentiation | regulation of apoptotic process | regulation of metabolic process | regulation of bicellular tight junction assembly | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | cellular component organization | positive regulation of epithelial cell migration | regulation of keratinocyte proliferation | response to stimulus | wound healing, spreading of cells | mesenchymal cell development | positive regulation of protein metabolic process | negative regulation of cell adhesion | response to stress | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | roof of mouth development | desmosome disassembly | cellular nitrogen compound metabolic process | negative regulation of metabolic process | regulation of anoikis | cartilage development | regulation of cell adhesion | regulation of steroid biosynthetic process | cellular biosynthetic process | regulation of morphogenesis of a branching structure | cell-cell signaling | regulation of steroid metabolic process | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage | cell surface receptor signaling pathway involved in cell-cell signaling | epiboly | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | locomotion | endocardial cushion development | system development | nitrogen compound metabolic process | regulation of signal transduction | positive regulation of organelle organization | Wnt signaling pathway | regulation of cartilage development | multicellular organism development | cell migration | regulation of intrinsic apoptotic signaling pathway | regulation of ossification | wound healing | positive regulation of chromosome organization | cardiac epithelial to mesenchymal transition | regulation of gene expression | positive regulation of chemotaxis | regulation of extrinsic apoptotic signaling pathway | nervous system process | endocardial cushion morphogenesis | regulation of stem cell proliferation | regulation of signal transduction by p53 class mediator | positive regulation of cellular metabolic process | cellular response to radiation | animal organ morphogenesis | negative regulation of chondrocyte differentiation | regulation of nitrogen compound metabolic process | regulation of cell migration | negative regulation of signal transduction by p53 class mediator | regulation of cellular component movement | regulation of transcription by RNA polymerase II | fat cell differentiation | pigmentation | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | morphogenesis of an epithelial sheet | positive regulation of cell differentiation | regulation of endothelial cell migration | negative regulation of extrinsic apoptotic signaling pathway | stem cell differentiation | response to platelet-derived growth factor | positive regulation of cell migration | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | mesenchyme morphogenesis | regulation of apoptotic signaling pathway | negative regulation of cell-cell adhesion | negative regulation of cell adhesion involved in substrate-bound cell migration | cell communication | regulation of cellular metabolic process | negative regulation of vitamin D receptor signaling pathway | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | sensory perception of sound | regulation of protein metabolic process | desmosome organization | heart development | negative regulation of stem cell proliferation | regulation of locomotion | regulation of RNA metabolic process | positive regulation of protein acetylation | regulation of lipid biosynthetic process | cell migration involved in heart development | cellular response to epidermal growth factor stimulus | negative regulation of epithelial cell proliferation | DNA-binding transcription factor activity | positive regulation of protein modification process | response to organic substance | tissue morphogenesis | response to wounding | regulation of animal organ morphogenesis | negative regulation of DNA damage response, signal transduction by p53 class mediator | regulation of intracellular signal transduction | positive regulation of peptidyl-lysine acetylation | negative regulation of intracellular signal transduction | substrate-dependent cell migration | anatomical structure development | cell surface receptor signaling pathway | negative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter | negative regulation of lipid metabolic process | metabolic process | mesenchymal cell differentiation | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | regulation of response to DNA damage stimulus | regulation of chondrocyte differentiation | nucleobase-containing compound metabolic process | organic substance metabolic process | cartilage morphogenesis | connective tissue development | negative regulation of intrinsic apoptotic signaling pathway | regulation of intrinsic apoptotic signaling pathway in response to DNA damage | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | positive regulation of histone modification | gene expression | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | cellular response to ionizing radiation | regulation of Wnt signaling pathway | regulation of chromosome organization | transcription, DNA-templated | positive regulation of endothelial cell migration | response to epidermal growth factor | stem cell development | anatomical structure formation involved in morphogenesis | negative regulation of cartilage development | sensory perception | regulation of epithelial cell migration | regulation of vitamin D receptor signaling pathway | regulation of cell communication | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | cell development | regulation of epithelial cell proliferation | regulation of cytokine production | endocardial cushion formation | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | positive regulation of fat cell differentiation | regulation of developmental process | developmental process | negative regulation of canonical Wnt signaling pathway | negative regulation of steroid metabolic process | white fat cell differentiation | regulation of chemokine production | regulation of histone acetylation | negative regulation of transcription by RNA polymerase II | regulation of cell junction assembly | positive regulation of histone acetylation | negative regulation of cell proliferation | regulation of cell-cell adhesion | neural crest cell differentiation | heterocycle metabolic process | regulation of lipid metabolic process | positive regulation of metabolic process | negative regulation of Wnt signaling pathway | skeletal system development | cellular metabolic process | cellular response to organic substance | regulation of cell death | positive regulation of cell motility | negative regulation of cell death | circulatory system development | neural crest cell development | negative regulation of cell differentiation | regulation of cellular component organization | negative regulation of steroid biosynthetic process | response to ionizing radiation | signal transduction | regulation of signaling | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process | cell-cell junction organization | regulation of chromatin organization

GO Cellular Component

chromosome | intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | chromatin | nuclear chromosome | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | nuclear chromatin | intracellular