QuickView for TAK1;jsessionid=2C0906AC942F2AE82BDC9B59871A7B0F (gene)
- Gene Symbol:
- Map3k7
Rattus norvegicus - Full name:
- mitogen activated protein kinase kinase kinase 7
- Synonyms:
- Tak1, mitogen-activated protein kinase kinase kinase 7, TGF-beta activated kinase 1
- Genomic Location:
- Chr 5: 48252628-48310292
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
E2F_02 , CREB_Q2 , CREB_Q4 , SP1_Q6 , E2F1_Q6 , GCGNNANTTCC_UNKNOWN , E2F1DP1_01 , E2F1DP2_01 , E2F4DP1_01 , E2F4DP2_01
- miRNA binding sites
(Source: TargetScan):
| Protein Names |
|---|
| No proteins found. |
GO Molecular Function
kinase binding | cation binding | protein kinase binding | magnesium ion binding | receptor tyrosine kinase binding | enzyme binding | ribonucleotide binding | nucleotide binding | signaling receptor binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | MAP kinase kinase kinase activity | purine nucleotide binding | identical protein binding | scaffold protein binding | ion binding | organic cyclic compound binding | protein tyrosine kinase binding | purine ribonucleoside triphosphate binding | protein binding | MAP kinase kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | protein serine/threonine/tyrosine kinase activity | drug binding | kinase activity | metal ion binding | heterocyclic compound binding | small molecule binding
GO Biological Process
positive regulation of immune response | RNA metabolic process | regulation of JUN kinase activity | regulation of T cell mediated immunity | intracellular signal transduction | morphogenesis of an epithelium | regulation of programmed cell death | peptidyl-amino acid modification | negative regulation of ripoptosome assembly involved in necroptotic process | regulation of autophagy | regulation of immune system process | negative regulation of cellular process | regulation of MAP kinase activity | histone modification | nervous system development | histone H3 acetylation | positive regulation of phosphate metabolic process | blood vessel morphogenesis | regulation of necroptotic process | cellular process | regulation of necrotic cell death | epithelial tube morphogenesis | chromatin organization | negative regulation of signaling | positive regulation of immune effector process | positive regulation of adaptive immune response | I-kappaB phosphorylation | positive regulation of protein kinase activity | negative regulation of apoptotic process | response to growth factor | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | tissue development | negative regulation of apoptotic signaling pathway | regulation of immune response | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of stress-activated MAPK cascade | regulation of protein complex assembly | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | epithelium development | positive regulation of T cell cytokine production | cellular aromatic compound metabolic process | cellular component organization | MAPK cascade | response to transforming growth factor beta | positive regulation of stress-activated protein kinase signaling cascade | response to stimulus | peptidyl-threonine phosphorylation | vasculature development | positive regulation of NIK/NF-kappaB signaling | JNK cascade | embryonic epithelial tube formation | positive regulation of immune system process | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | response to stress | cellular nitrogen compound biosynthetic process | tube morphogenesis | protein serine/threonine kinase activity | programmed cell death | epithelial tube formation | cardiovascular system development | peptidyl-lysine acetylation | cellular nitrogen compound metabolic process | negative regulation of necroptotic process | regulation of macroautophagy | negative regulation of metabolic process | positive regulation of protein serine/threonine kinase activity | protein modification process | cellular biosynthetic process | embryo development | macromolecule modification | activation of protein kinase activity | blood vessel development | stress-activated protein kinase signaling cascade | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | apoptotic process | system development | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | protein acetylation | regulation of MAPK cascade | phosphorus metabolic process | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | anoikis | regulation of gene expression | cellular response to stress | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | MAP kinase kinase kinase activity | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | positive regulation of JNK cascade | positive regulation of intracellular signal transduction | neural tube formation | regulation of T cell cytokine production | histone acetylation | internal peptidyl-lysine acetylation | biosynthetic process | stress-activated MAPK cascade | neural tube development | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | angiogenesis | phosphorylation | regulation of apoptotic signaling pathway | activation of NF-kappaB-inducing kinase activity | protein phosphorylation | phosphate-containing compound metabolic process | chordate embryonic development | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | transmembrane receptor protein serine/threonine kinase signaling pathway | activation of MAPKK activity | negative regulation of necrotic cell death | regulation of cytokine production involved in immune response | regulation of NIK/NF-kappaB signaling | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | embryonic morphogenesis | positive regulation of molecular function | cellular response to transforming growth factor beta stimulus | activation of MAPK activity | protein metabolic process | positive regulation of protein modification process | response to organic substance | tissue morphogenesis | regulation of kinase activity | MAP kinase kinase activity | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | metabolic process | regulation of adaptive immune response | regulation of RNA biosynthetic process | negative regulation of programmed cell death | positive regulation of cytokine production involved in immune response | peptidyl-lysine modification | morphogenesis of embryonic epithelium | nucleobase-containing compound metabolic process | protein kinase activity | negative regulation of protein complex assembly | organic substance metabolic process | cell death | gene expression | positive regulation of kinase activity | regulation of phosphate metabolic process | positive regulation of autophagy | transcription, DNA-templated | positive regulation of cytokine production | positive regulation of macroautophagy | regulation of JNK cascade | positive regulation of MAPK cascade | positive regulation of T cell mediated immunity | transforming growth factor beta receptor signaling pathway | anatomical structure formation involved in morphogenesis | regulation of stress-activated MAPK cascade | regulation of cell communication | negative regulation of signal transduction | signaling | positive regulation of I-kappaB kinase/NF-kappaB signaling | covalent chromatin modification | regulation of transcription, DNA-templated | I-kappaB kinase/NF-kappaB signaling | internal protein amino acid acetylation | positive regulation of phosphorylation | cellular protein metabolic process | regulation of cytokine production | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | positive regulation of MAP kinase activity | protein serine/threonine/tyrosine kinase activity | kinase activity | developmental process | organelle organization | cellular protein modification process | positive regulation of interleukin-2 production | tube development | regulation of reactive oxygen species metabolic process | NIK/NF-kappaB signaling | heterocycle metabolic process | tube formation | positive regulation of JUN kinase activity | positive regulation of metabolic process | chromosome organization | cellular metabolic process | cellular response to organic substance | regulation of cell death | negative regulation of cell death | circulatory system development | regulation of I-kappaB kinase/NF-kappaB signaling | regulation of cellular component organization | negative regulation of reactive oxygen species metabolic process | positive regulation of signaling | signal transduction | regulation of signaling | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | synapse | catalytic complex | protein kinase complex | cell | nuclear lumen | histone acetyltransferase complex | cytoplasm | intracellular organelle | IkappaB kinase complex | protein-containing complex | postsynapse | nucleoplasm | plasma membrane | transferase complex | postsynaptic density | asymmetric synapse | serine/threonine protein kinase complex | membrane-bounded organelle | nucleus | organelle | postsynaptic specialization | cell periphery | membrane-enclosed lumen | protein acetyltransferase complex | cytosol | intracellular | membrane | Ada2/Gcn5/Ada3 transcription activator complex
