QuickView for TER94;jsessionid=DCAD6374D92ACB07281E0D5163D1D634 (gene)
- Gene Symbol:
- VCP
Bos taurus - Full name:
- valosin-containing protein
- Synonyms:
- MGC128142, p97
- Genomic Location:
- Chr 8: 61976874-61991606
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Schizosaccharomyces pombe , Danio rerio , Gallus gallus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
CP2_01 , NFY_Q6 , TCF11MAFG_01 , TCF11_01 , NFY_01 , FREAC7_01 , ZF5_B , ATF6_01 , ALPHACP1_01 , GCTNWTTGK_UNKNOWN
GO Molecular Function
MHC protein binding | deubiquitinase activator activity | ADP binding | enzyme activator activity | K48-linked polyubiquitin modification-dependent protein binding | enzyme binding | protein-containing complex binding | ribonucleotide binding | lipid binding | peptidase activator activity | nucleotide binding | signaling receptor binding | hydrolase activity | carbohydrate derivative binding | ubiquitin-specific protease binding | ATPase activity | pyrophosphatase activity | molecular function regulator | catalytic activity | polyubiquitin modification-dependent protein binding | protein domain specific binding | ATP binding | ubiquitin-like protein ligase binding | anion binding | adenyl nucleotide binding | BAT3 complex binding | modification-dependent protein binding | nucleoside-triphosphatase activity | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | protein phosphatase binding | ubiquitin protein ligase binding | hydrolase activity, acting on acid anhydrides | MHC class I protein binding | purine ribonucleotide binding | enzyme regulator activity | adenyl ribonucleotide binding | drug binding | protease binding | phosphatase binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding
GO Biological Process
purine ribonucleotide metabolic process | double-strand break repair | protein hexamerization | regulation of cysteine-type endopeptidase activity | response to endoplasmic reticulum stress | deubiquitinase activator activity | positive regulation of cellular component organization | nucleoside phosphate catabolic process | positive regulation of ATP metabolic process | enzyme activator activity | positive regulation of apoptotic process | proteolysis | macroautophagy | regulation of programmed cell death | peptidyl-amino acid modification | translesion synthesis | establishment of localization | regulation of aerobic respiration | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | response to misfolded protein | positive regulation of protein catabolic process | organophosphate catabolic process | ER-associated misfolded protein catabolic process | positive regulation of phosphate metabolic process | intracellular transport | positive regulation of oxidative phosphorylation | positive regulation of cellular biosynthetic process | cellular process | organic substance catabolic process | endosome transport via multivesicular body sorting pathway | localization | proteolysis involved in cellular protein catabolic process | protein transport | regulation of ubiquitin-specific protease activity | regulation of mitochondrial membrane potential | nucleotide metabolic process | positive regulation of membrane potential | ribose phosphate metabolic process | macromolecule localization | postreplication repair | regulation of proteolysis | nucleoside triphosphate metabolic process | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | ribonucleotide metabolic process | regulation of canonical Wnt signaling pathway | establishment of localization in cell | interspecies interaction between organisms | regulation of oxidative phosphorylation | glycoprotein biosynthetic process | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | regulation of protein complex assembly | peptidase activator activity | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | response to topologically incorrect protein | cellular aromatic compound metabolic process | protein N-linked glycosylation via asparagine | cellular component organization | viral life cycle | cellular response to topologically incorrect protein | positive regulation of cellular protein catabolic process | response to stimulus | lysosomal transport | purine nucleotide metabolic process | positive regulation of protein metabolic process | positive regulation of peptidase activity | endosomal transport | regulation of cellular protein catabolic process | response to stress | intracellular protein transport | vacuolar transport | cellular nitrogen compound biosynthetic process | positive regulation of cysteine-type endopeptidase activity | positive regulation of proteolysis involved in cellular protein catabolic process | cellular protein catabolic process | cellular localization | positive regulation of proteolysis | cellular nitrogen compound metabolic process | proteasomal protein catabolic process | carbohydrate derivative biosynthetic process | cofactor metabolic process | cellular component assembly | protein modification process | macromolecule glycosylation | cellular biosynthetic process | macromolecule modification | nucleobase-containing compound catabolic process | molecular function regulator | DNA repair | regulation of membrane potential | response to nitrogen compound | NADH metabolic process | nitrogen compound metabolic process | regulation of signal transduction | regulation of peptidase activity | phosphorus metabolic process | cellular response to DNA damage stimulus | protein complex oligomerization | regulation of catalytic activity | regulation of phosphorylation | regulation of protein deubiquitination | endosome to lysosome transport | DNA biosynthetic process | organic substance transport | cellular response to stress | protein catabolic process | organophosphate metabolic process | viral genome replication | positive regulation of cellular metabolic process | positive regulation of ATP biosynthetic process | positive regulation of protein deubiquitination | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | regulation of cysteine-type endopeptidase activity involved in apoptotic process | small molecule metabolic process | peptide transport | positive regulation of protein complex assembly | vesicle-mediated transport | positive regulation of ubiquitin-specific protease activity | positive regulation of hydrolase activity | nucleobase-containing small molecule metabolic process | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | positive regulation of proteasomal protein catabolic process | positive regulation of endopeptidase activity | nucleotide catabolic process | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | phosphate-containing compound metabolic process | autophagy | positive regulation of Lys63-specific deubiquitinase activity | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | aromatic compound catabolic process | positive regulation of protein K63-linked deubiquitination | viral process | proteasome-mediated ubiquitin-dependent protein catabolic process | drug metabolic process | positive regulation of molecular function | regulation of proteasomal ubiquitin-dependent protein catabolic process | ERAD pathway | protein-containing complex assembly | protein metabolic process | positive regulation of protein modification process | response to organic substance | protein ubiquitination | regulation of cellular respiration | DNA metabolic process | cellular macromolecule catabolic process | metabolic process | activation of cysteine-type endopeptidase activity involved in apoptotic process | positive regulation of ubiquitin-dependent protein catabolic process | regulation of protein catabolic process | protein quality control for misfolded or incompletely synthesized proteins | regulation of proteasomal protein catabolic process | cellular protein localization | endoplasmic reticulum stress-induced pre-emptive quality control | amide transport | positive regulation of cell death | nucleobase-containing compound metabolic process | positive regulation of cellular component biogenesis | organic substance metabolic process | positive regulation of programmed cell death | protein modification by small protein conjugation or removal | regulation of Wnt signaling pathway | regulation of ATP metabolic process | regulation of phosphate metabolic process | establishment of protein localization | positive regulation of canonical Wnt signaling pathway | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | regulation of cell communication | aggresome assembly | protein localization | protein-containing complex disassembly | positive regulation of phosphorylation | cellular protein metabolic process | enzyme regulator activity | protein N-linked glycosylation | regulation of endopeptidase activity | cellular macromolecule localization | cellular macromolecule biosynthetic process | nicotinamide nucleotide metabolic process | cellular protein modification process | NAD metabolic process | carbohydrate derivative metabolic process | DNA synthesis involved in DNA repair | response to organonitrogen compound | heterocycle metabolic process | protein glycosylation | endosome to lysosome transport via multivesicular body sorting pathway | ubiquitin-dependent ERAD pathway | glycosylation | regulation of generation of precursor metabolites and energy | positive regulation of metabolic process | cellular response to misfolded protein | positive regulation of Wnt signaling pathway | cellular metabolic process | ATP metabolic process | cellular response to organic substance | regulation of cell death | modification-dependent protein catabolic process | glycoprotein metabolic process | regulation of ubiquitin-dependent protein catabolic process | protein exit from endoplasmic reticulum | autophagosome maturation | positive regulation of mitochondrial membrane potential | regulation of cellular component organization | retrograde protein transport, ER to cytosol | multivesicular body sorting pathway | positive regulation of signaling | regulation of signaling | flavin adenine dinucleotide catabolic process | macromolecule metabolic process | regulation of phosphorus metabolic process
GO Cellular Component
site of DNA damage | chromosome | intracellular membrane-bounded organelle | catalytic complex | cell | nuclear lumen | Derlin-1 retrotranslocation complex | cytoplasm | proteasome complex | VCP-NSFL1C complex | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | endomembrane system | endoplasmic reticulum membrane | nucleoplasm | lipid droplet | perinuclear region of cytoplasm | site of double-strand break | membrane-bounded organelle | nucleus | organelle | VCP-NPL4-UFD1 AAA ATPase complex | membrane-enclosed lumen | ATPase complex | cytosol | intracellular | myelin sheath | membrane
