QuickView for TIMP3;jsessionid=4B9DC4AE20B396428B1B9E1357176C89;jsessionid=BB1F3F251CA5A4C725B96D1D55F5AB84 (gene)
- Gene Symbol:
- Timp3
Mus musculus - Full name:
- tissue inhibitor of metalloproteinase 3
- Synonyms:
- Timp-3, metalloproteinase inhibitor 3, tissue inhibitor of metalloproteinases 3
- Genomic Location:
- Chr 10: 85763157-85812250
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
AACTTT_UNKNOWN , IK3_01 , MYCMAX_02 , PAX5_01 , SP1_Q6 , RREB1_01 , VDR_Q3 , ZIC2_01 , ZIC3_01 , CEBPDELTA_Q6
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-1 , Predicted Gene Targets for miR-101 , Predicted Gene Targets for miR-144 , Predicted Gene Targets for miR-181 , Predicted Gene Targets for miR-20 , Predicted Gene Targets for miR-21 , Predicted Gene Targets for miR-221 , Predicted Gene Targets for miR-30 , Predicted Gene Targets for miR-299-3p , Predicted Gene Targets for miR-384
GO Molecular Function
endopeptidase inhibitor activity | cation binding | enzyme binding | enzyme inhibitor activity | molecular function regulator | ion binding | protein binding | metalloendopeptidase inhibitor activity | peptidase inhibitor activity | enzyme regulator activity | protease binding | metal ion binding
GO Biological Process
negative regulation of metalloendopeptidase activity | regulation of ERK1 and ERK2 cascade | negative regulation of phosphorylation | negative regulation of membrane protein ectodomain proteolysis | endopeptidase inhibitor activity | negative regulation of MAPK cascade | response to cytokine | positive regulation of apoptotic process | regulation of programmed cell death | response to hormone | negative regulation of cellular process | negative regulation of protein phosphorylation | negative regulation of proteolysis | cellular process | negative regulation of signaling | regulation of proteolysis | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors | negative regulation of cellular metabolic process | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | response to stimulus | enzyme inhibitor activity | negative regulation of metabolic process | negative regulation of ERK1 and ERK2 cascade | molecular function regulator | regulation of signal transduction | negative regulation of phosphate metabolic process | negative regulation of catalytic activity | regulation of peptidase activity | regulation of MAPK cascade | regulation of catalytic activity | regulation of phosphorylation | negative regulation of peptidase activity | regulation of extrinsic apoptotic signaling pathway | negative regulation of metallopeptidase activity | regulation of nitrogen compound metabolic process | regulation of cellular protein metabolic process | regulation of apoptotic signaling pathway | positive regulation of extrinsic apoptotic signaling pathway | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | response to organic substance | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | regulation of protein catabolic process | positive regulation of cell death | negative regulation of cellular protein metabolic process | positive regulation of programmed cell death | regulation of phosphate metabolic process | positive regulation of TRAIL-activated apoptotic signaling pathway | negative regulation of protein catabolic process | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | regulation of extrinsic apoptotic signaling pathway via death domain receptors | metalloendopeptidase inhibitor activity | peptidase inhibitor activity | enzyme regulator activity | regulation of endopeptidase activity | negative regulation of hydrolase activity | cellular response to organic substance | regulation of cell death | positive regulation of apoptotic signaling pathway | positive regulation of signaling | regulation of signaling | negative regulation of endopeptidase activity | regulation of phosphorus metabolic process
GO Cellular Component
extracellular matrix | basement membrane | cell | cytoplasm | collagen-containing extracellular matrix | extracellular region | extracellular space | intracellular
