QuickView for TK25;jsessionid=8C2ED186389585582270DBD8CC23FC32;jsessionid=9822ABC37A14398E55F1E45F2152D1EB (gene)
- Gene Symbol:
- Fgfr2
Mus musculus - Full name:
- fibroblast growth factor receptor 2
- Synonyms:
- AU043015, AW556123, Bek, Fgfr-2, Fgfr-7, Fgfr7, KGFR, KGFRTr, svs, fibroblast growth factor receptor 2, keratinocyte growth factor receptor
- Genomic Location:
- Chr 7: 137305965-137410322
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Bos taurus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
AAANWWTGC_UNKNOWN , AACTTT_UNKNOWN , SOX5_01 , TST1_01 , BRN2_01 , AGCYRWTTC_UNKNOWN , SRY_02 , OCT1_05 , OCT_C , OCT1_07
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-125 , Predicted Gene Targets for miR-153 , Predicted Gene Targets for miR-218 , Predicted Gene Targets for miR-22 , Predicted Gene Targets for miR-223 , Predicted Gene Targets for miR-338 , Predicted Gene Targets for miR-369-3p , Predicted Gene Targets for miR-494 , Predicted Gene Targets for miR-124a , Predicted Gene Targets for miR-124u
GO Molecular Function
transmembrane receptor protein tyrosine kinase activity | fibroblast growth factor-activated receptor activity | transmembrane signaling receptor activity | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | growth factor binding | catalytic activity | fibroblast growth factor binding | ATP binding | anion binding | adenyl nucleotide binding | signaling receptor activity | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | heparin binding | purine ribonucleoside triphosphate binding | protein tyrosine kinase activity | protein binding | protein homodimerization activity | protein dimerization activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | glycosaminoglycan binding | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding
GO Biological Process
positive regulation of smooth muscle cell proliferation | regulation of ERK1 and ERK2 cascade | brain development | limb development | molting cycle | branch elongation involved in salivary gland morphogenesis | cell morphogenesis | inner ear morphogenesis | ventricular cardiac muscle tissue morphogenesis | endodermal digestive tract morphogenesis | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | fibroblast growth factor receptor signaling pathway involved in hemopoiesis | branching morphogenesis of a nerve | epidermis morphogenesis | neuron projection morphogenesis | cranial skeletal system development | developmental process involved in reproduction | muscle tissue development | mammary gland duct morphogenesis | prostate gland growth | otic vesicle development | morphogenesis of an epithelium | positive regulation of striated muscle tissue development | regulation of programmed cell death | fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development | peptidyl-amino acid modification | transmembrane receptor protein tyrosine kinase activity | eye development | branching involved in salivary gland morphogenesis | establishment of localization | mammary gland bud morphogenesis | negative regulation of cellular process | positive regulation of developmental process | negative regulation of RNA biosynthetic process | bone development | regulation of heart growth | otic vesicle formation | cell differentiation | positive regulation of epithelial cell proliferation | bone mineralization | respiratory tube development | nervous system development | epithelial to mesenchymal transition | multicellular organism growth | organ growth | cell part morphogenesis | neurogenesis | positive regulation of phosphate metabolic process | peptidyl-tyrosine phosphorylation | regulation of organelle organization | generation of neurons | mesenchyme development | salivary gland morphogenesis | intracellular transport | blood vessel morphogenesis | regulation of cardiac muscle cell proliferation | pattern specification process | positive regulation of cellular biosynthetic process | cellular process | regulation of branching involved in prostate gland morphogenesis | regulation of epithelial cell proliferation involved in lung morphogenesis | establishment of organelle localization | localization | cell projection morphogenesis | epithelial tube morphogenesis | limb morphogenesis | odontogenesis | heart morphogenesis | negative regulation of signaling | developmental growth | neuron development | cranial suture morphogenesis | central nervous system neuron differentiation | reproductive system development | fibroblast growth factor-activated receptor activity | regulation of mitotic nuclear division | mammary gland bud formation | immune system development | negative regulation of nucleic acid-templated transcription | regulation of striated muscle tissue development | glandular epithelial cell differentiation | negative regulation of apoptotic process | digestive tract morphogenesis | regulation of cell cycle | response to growth factor | positive regulation of catalytic activity | regulation of multicellular organism growth | positive regulation of nitrogen compound metabolic process | forebrain neuron differentiation | positive regulation of cell division | regulation of canonical Wnt signaling pathway | regulation of smoothened signaling pathway | establishment of localization in cell | negative regulation of cellular metabolic process | mammary gland specification | tissue development | regulation of cell differentiation | muscle structure development | ventricular septum morphogenesis | regulation of cellular process | regulation of apoptotic process | labyrinthine layer morphogenesis | regulation of metabolic process | organelle localization | forebrain ventricular zone progenitor cell division | positive regulation of cellular protein metabolic process | epithelium development | coronary vasculature morphogenesis | cellular component organization | prostate gland epithelium morphogenesis | epithelial tube branching involved in lung morphogenesis | regulation of cell division | urogenital system development | mammary gland morphogenesis | head development | muscle organ morphogenesis | response to stimulus | lacrimal gland development | vasculature development | cell morphogenesis involved in neuron differentiation | lung lobe morphogenesis | respiratory system development | cellular response to fibroblast growth factor stimulus | positive regulation of protein metabolic process | gland morphogenesis | craniofacial suture morphogenesis | regulation of cell proliferation | tube morphogenesis | branching involved in labyrinthine layer morphogenesis | cardiac muscle tissue development | vasculogenesis involved in coronary vascular morphogenesis | muscle tissue morphogenesis | epithelial cell development | programmed cell death | epithelial tube formation | reproduction | cellular localization | embryonic skeletal system development | squamous basal epithelial stem cell differentiation involved in prostate gland acinus development | cardiovascular system development | embryonic digestive tract morphogenesis | cardiac ventricle morphogenesis | midbrain development | positive regulation of lipase activity | axis elongation | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | hemopoiesis | protein modification process | kidney development | embryo development | regulation of morphogenesis of a branching structure | macromolecule modification | cell-cell signaling | mammary gland formation | pyramidal neuron development | embryonic placenta development | blood vessel development | regulation of nucleic acid-templated transcription | somatic stem cell division | central nervous system neuron development | lung alveolus development | apoptotic process | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | ureteric bud development | multicellular organism development | regulation of MAPK cascade | neuroblast proliferation | phosphorus metabolic process | mammary gland development | epithelial cell differentiation involved in prostate gland development | positive regulation of muscle organ development | regulation of catalytic activity | forebrain neuron development | regulation of phosphorylation | fibroblast growth factor receptor signaling pathway | hair follicle morphogenesis | embryonic digestive tract development | positive regulation of cell cycle | regulation of gene expression | lateral sprouting from an epithelium | stem cell proliferation | ventricular zone neuroblast division | kidney epithelium development | axon development | outflow tract morphogenesis | branching involved in prostate gland morphogenesis | stem cell division | regulation of fibroblast growth factor receptor signaling pathway | coronary vasculature development | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | neuromuscular junction development | regulation of smooth muscle cell differentiation | animal organ morphogenesis | specification of animal organ identity | limb bud formation | protein autophosphorylation | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | positive regulation of intracellular signal transduction | vesicle-mediated transport | regulation of transcription by RNA polymerase II | morphogenesis of an epithelial fold | synapse organization | axonogenesis | positive regulation of cell proliferation in bone marrow | positive regulation of hydrolase activity | negative regulation of mitotic nuclear division | stem cell differentiation | establishment of vesicle localization | cell proliferation | positive regulation of cardiac muscle cell proliferation | labyrinthine layer development | cell division | neuronal stem cell division | regulation of cellular protein metabolic process | angiogenesis | phosphorylation | mesonephric epithelium development | cardiac septum morphogenesis | mesenchymal cell differentiation involved in lung development | digestive tract development | regulation of phospholipase activity | epidermis development | skin development | protein phosphorylation | cell morphogenesis involved in differentiation | bud elongation involved in lung branching | mesonephros development | post-embryonic development | phosphate-containing compound metabolic process | sensory organ development | chordate embryonic development | animal organ formation | striated muscle tissue development | cardiac muscle tissue morphogenesis | cell communication | regulation of cellular metabolic process | skeletal system morphogenesis | regulation of protein metabolic process | positive regulation of signal transduction | vasculogenesis | inner ear development | pyramidal neuron differentiation | heart development | limbic system development | positive regulation of cell proliferation | regulation of protein phosphorylation | bone morphogenesis | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | renal system development | negative regulation of apoptotic process in bone marrow | regulation of cellular response to growth factor stimulus | embryonic morphogenesis | regulation of mitotic cell cycle | cell proliferation in forebrain | protein tyrosine kinase activity | positive regulation of molecular function | neuron differentiation | embryonic organ morphogenesis | embryonic cranial skeleton morphogenesis | positive regulation of organ growth | ventricular septum development | negative regulation of epithelial cell proliferation | protein metabolic process | regionalization | cardiac ventricle development | positive regulation of protein modification process | regulation of growth | hair cycle | response to organic substance | gland development | regulation of cardiac muscle tissue development | tissue morphogenesis | coronal suture morphogenesis | digestive system development | branching morphogenesis of an epithelial tube | epithelial cell proliferation | regulation of animal organ morphogenesis | regulation of intracellular signal transduction | ventricular cardiac muscle tissue development | anatomical structure development | developmental growth involved in morphogenesis | branch elongation of an epithelium | cell surface receptor signaling pathway | embryonic skeletal system morphogenesis | cell projection organization | metabolic process | cell fate commitment | mesenchymal cell differentiation | regulation of RNA biosynthetic process | prostate epithelial cord elongation | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | embryonic organ development | lens fiber cell development | negative regulation of mitotic cell cycle | ear development | hair cycle process | forebrain generation of neurons | morphogenesis of embryonic epithelium | protein kinase activity | neuron projection development | mesenchymal cell proliferation | organic substance metabolic process | cell death | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | lung-associated mesenchyme development | forebrain development | positive regulation of ERK1 and ERK2 cascade | skin epidermis development | regulation of Wnt signaling pathway | neural precursor cell proliferation | regulation of phosphate metabolic process | biomineral tissue development | mammary gland epithelium development | prostate gland morphogenesis | positive regulation of muscle tissue development | positive regulation of phospholipase activity | orbitofrontal cortex development | positive regulation of MAPK cascade | lung development | morphogenesis of a branching epithelium | fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow | camera-type eye development | positive regulation of canonical Wnt signaling pathway | anatomical structure formation involved in morphogenesis | neuroblast division | negative regulation of cell cycle | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis | regulation of cell communication | negative regulation of signal transduction | positive regulation of developmental growth | signaling | positive regulation of growth | regulation of transcription, DNA-templated | cell development | regulation of developmental growth | synaptic vesicle localization | regulation of epithelial cell proliferation | positive regulation of phosphorylation | cellular protein metabolic process | morphogenesis of a branching structure | anatomical structure morphogenesis | prostate gland development | regulation of organ growth | reproductive structure development | regulation of developmental process | forebrain neuroblast division | epithelial cell proliferation involved in salivary gland morphogenesis | kinase activity | regulation of mesenchymal cell proliferation | developmental process | regulation of muscle cell differentiation | cardiac septum development | cellular protein modification process | negative regulation of transcription by RNA polymerase II | tube development | positive regulation of transcription, DNA-templated | membranous septum morphogenesis | negative regulation of cell proliferation | mesenchymal cell proliferation involved in lung development | response to fibroblast growth factor | positive regulation of mesenchymal cell proliferation | positive regulation of nucleic acid-templated transcription | positive regulation of heart growth | lung morphogenesis | epithelial cell differentiation | embryonic placenta morphogenesis | positive regulation of transcription by RNA polymerase II | cardiac chamber development | tube formation | fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow | regulation of cell fate commitment | central nervous system development | transmembrane receptor protein tyrosine kinase signaling pathway | in utero embryonic development | positive regulation of metabolic process | ossification | vesicle localization | skeletal system development | immune system process | positive regulation of Wnt signaling pathway | lung lobe development | cellular metabolic process | hematopoietic or lymphoid organ development | negative regulation of cell cycle process | placenta development | synaptic vesicle transport | cellular response to organic substance | exocrine system development | regulation of cell death | positive regulation of cardiac muscle tissue development | regulation of smooth muscle cell proliferation | salivary gland development | lens fiber cell differentiation | negative regulation of cell death | circulatory system development | ear morphogenesis | fibroblast growth factor receptor signaling pathway involved in mammary gland specification | regulation of cellular component organization | lens development in camera-type eye | muscle organ development | otic vesicle morphogenesis | positive regulation of signaling | hair follicle development | positive regulation of epithelial cell proliferation involved in lung morphogenesis | signal transduction | regulation of signaling | mesonephric tubule development | positive regulation of gene expression | embryonic pattern specification | outflow tract septum morphogenesis | cellular response to growth factor stimulus | regulation of muscle organ development | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | synapse | extracellular matrix | cytoplasmic vesicle | cell | nuclear lumen | intrinsic component of membrane | cytoplasm | intracellular organelle | receptor complex | Golgi apparatus | protein-containing complex | endomembrane system | nucleoplasm | plasma membrane | vesicle | cytoplasmic region | integral component of plasma membrane | extracellular region | cell cortex | membrane-bounded organelle | nucleus | organelle | cell periphery | excitatory synapse | membrane-enclosed lumen | intracellular vesicle | cell surface | intracellular | membrane | intrinsic component of plasma membrane
