QuickView for TNF-R55;jsessionid=B06139021A823CEF84DFF5C295EF8075;jsessionid=20D56E783251E5ABD8E0F1B23D1288D6 (gene)
- Gene Symbol:
- Tnfrsf1a
Rattus norvegicus - Full name:
- TNF receptor superfamily member 1A
- Synonyms:
- TNFR-1, Tnfr1, tumor necrosis factor receptor superfamily member 1A, TNF-R1, TNF-RI, TNFR-I, p55, p60, tumor necrosis factor receptor 1, tumor necrosis factor receptor superfamily, member 1a, tumor necrosis factor receptor type I
- Genomic Location:
- Chr 4: 162172563-162185252
- Description:
-
may play a role in TNFalpha mediated inflammatory response to spinal cord injury
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Bos taurus , Canis lupus familiaris , Danio rerio , Gallus gallus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
cytokine binding | transmembrane signaling receptor activity | enzyme binding | protein-containing complex binding | tumor necrosis factor binding | death receptor activity | signaling receptor activity | identical protein binding | protein binding | tumor necrosis factor-activated receptor activity | protease binding
GO Biological Process
regulation of muscle system process | positive regulation of macromolecule biosynthetic process | regulation of intracellular protein transport | response to cytokine | response to lipopolysaccharide | protein localization to cell periphery | regulation of cellular localization | intracellular signal transduction | positive regulation of apoptotic process | regulation of cell development | regulation of localization | regulation of programmed cell death | positive regulation of peptidyl-tyrosine phosphorylation | defense response to other organism | response to hormone | negative regulation of cellular process | positive regulation of developmental process | cellular response to tumor necrosis factor | regulation of protein import | defense response | intrinsic apoptotic signaling pathway in response to DNA damage | response to drug | regulation of extracellular matrix organization | pulmonary valve development | positive regulation of phosphate metabolic process | response to antibiotic | regulation of neuron death | positive regulation of cellular biosynthetic process | cellular process | negative regulation of inflammatory response | localization | response to estradiol | macromolecule localization | negative regulation of apoptotic process | negative regulation of secretion | response to hypoxia | regulation of tyrosine phosphorylation of STAT protein | positive regulation of nitrogen compound metabolic process | regulation of cell differentiation | intrinsic apoptotic signaling pathway | negative regulation of muscle hypertrophy | regulation of angiogenesis | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | positive regulation of cellular protein metabolic process | cellular component organization | cellular lipid metabolic process | positive regulation of tumor necrosis factor production | regulation of vasculature development | response to stimulus | regulation of cellular protein localization | cellular response to mechanical stimulus | monocarboxylic acid metabolic process | regulation of peptidyl-tyrosine phosphorylation | negative regulation of extracellular matrix organization | positive regulation of protein metabolic process | response to stress | positive regulation of JAK-STAT cascade | positive regulation of cellular protein localization | regulation of epithelial cell differentiation | programmed cell death | cellular localization | response to alcohol | response to molecule of bacterial origin | negative regulation of transport | cellular response to organic cyclic compound | regulation of protein transport | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular component assembly | regulation of peptide transport | regulation of intracellular transport | response to ethanol | regulation of nucleic acid-templated transcription | response to nitrogen compound | apoptotic process | cellular response to hormone stimulus | response to external biotic stimulus | system development | response to oxygen levels | regulation of signal transduction | negative regulation of secretion by cell | negative regulation of interleukin-6 production | multicellular organism development | response to amino acid | positive regulation of inflammatory response | cellular response to DNA damage stimulus | protein complex oligomerization | lipid metabolic process | regulation of phosphorylation | protein localization to plasma membrane | regulation of gene expression | protein localization to membrane | cellular response to stress | response to lipid | death receptor activity | positive regulation of intracellular protein transport | negative regulation of cytokine production | regulation of protein import into nucleus, translocation | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | negative regulation of cardiac muscle hypertrophy | regulation of protein localization to nucleus | regulation of nitrogen compound metabolic process | small molecule metabolic process | positive regulation of STAT cascade | cytokine-mediated signaling pathway | positive regulation of intracellular signal transduction | regulation of transcription by RNA polymerase II | negative regulation of extracellular matrix constituent secretion | cellular response to cytokine stimulus | positive regulation of protein localization to nucleus | regulation of cellular protein metabolic process | positive regulation of neuron death | response to toxic substance | regulation of tumor necrosis factor production | response to bacterium | cell communication | regulation of cellular metabolic process | regulation of neuron apoptotic process | positive regulation of tyrosine phosphorylation of STAT protein | regulation of establishment of endothelial barrier | semi-lunar valve development | inflammatory response | regulation of protein metabolic process | positive regulation of signal transduction | heart development | defense response to bacterium | positive regulation of establishment of protein localization | regulation of protein phosphorylation | regulation of RNA metabolic process | positive regulation of transport | apoptotic signaling pathway | positive regulation of apoptotic process involved in development | carboxylic acid metabolic process | regulation of nucleocytoplasmic transport | protein-containing complex assembly | heart valve development | regulation of cardiac muscle hypertrophy | regulation of establishment of protein localization | positive regulation of protein modification process | response to organic substance | regulation of protein import into nucleus | regulation of JAK-STAT cascade | response to wounding | response to mechanical stimulus | regulation of intracellular signal transduction | positive regulation of neuron apoptotic process | anatomical structure development | cell surface receptor signaling pathway | metabolic process | regulation of RNA biosynthetic process | negative regulation of programmed cell death | cellular protein localization | prostaglandin metabolic process | regulation of secretion | positive regulation of cell death | organic substance metabolic process | cell death | negative regulation of gene expression | tumor necrosis factor-activated receptor activity | animal organ development | positive regulation of programmed cell death | tumor necrosis factor-mediated signaling pathway | regulation of phosphate metabolic process | response to alkaloid | fatty acid metabolic process | positive regulation of cytokine production | positive regulation of intracellular transport | positive regulation of protein transport | icosanoid metabolic process | cellular response to estradiol stimulus | positive regulation of protein import into nucleus, translocation | regulation of cell communication | signaling | positive regulation of I-kappaB kinase/NF-kappaB signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | protein localization | organic acid metabolic process | positive regulation of phosphorylation | regulation of cytokine production | protein heterooligomerization | cellular macromolecule localization | positive regulation of protein import into nucleus | response to biotic stimulus | regulation of developmental process | developmental process | positive regulation of protein import | regulation of transport | positive regulation of transcription, DNA-templated | aortic valve development | regulation of endothelial cell differentiation | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | positive regulation of transcription by RNA polymerase II | regulation of apoptotic process involved in development | positive regulation of metabolic process | cellular metabolic process | response to tumor necrosis factor | positive regulation of apoptotic process involved in morphogenesis | cellular response to organic substance | regulation of protein localization | regulation of cell death | negative regulation of cell death | regulation of interleukin-6 production | circulatory system development | regulation of inflammatory response | positive regulation of nucleocytoplasmic transport | positive regulation of angiogenesis | regulation of I-kappaB kinase/NF-kappaB signaling | regulation of cellular component organization | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | synapse | neuron projection | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | receptor complex | membrane microdomain | Golgi apparatus | protein-containing complex | cell projection | endomembrane system | membrane raft | mitochondrion | Golgi membrane | extracellular region | membrane-bounded organelle | nucleus | organelle | extracellular space | axon | cytosol | cell surface | intracellular | membrane
