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QuickView for TNFSF4;jsessionid=48582D5F81AEBB11C49122368C01EDDA;jsessionid=D599B0360687E7F7C8054860CD23E44B (gene)


Gene Symbol:
Tnfsf4 Mus musculus Mus musculus
Full name:
tumor necrosis factor (ligand) superfamily, member 4
Synonyms:
Ath-1, Ath1, CD134L, OX-40L, Ox40l, TXGP1, Tnlg2b, Txgp1l, gp34, tumor necrosis factor ligand superfamily member 4, OX40 ligand, atherosclerosis 1, tax-transcriptionally activated glycoprotein 1 ligand, tumor necrosis factor ligand 2b
Genomic Location:
Chr 1: 163325589-163348337
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_009452
Protein Names
P43488
B6DXE3



GO Molecular Function

signaling receptor binding | cytokine receptor binding | molecular function regulator | tumor necrosis factor receptor binding | protein binding | receptor regulator activity | receptor ligand activity | cytokine activity | tumor necrosis factor receptor superfamily binding

GO Biological Process

positive regulation of immune response | negative regulation of lymphocyte differentiation | negative regulation of leukocyte activation | regulation of T cell mediated immunity | positive regulation of locomotion | response to virus | negative regulation of immune system process | cellular response to nitrogen dioxide | regulation of B cell activation | CD4-positive, alpha-beta T cell activation | response to lipopolysaccharide | negative regulation of peptide secretion | regulation of localization | regulation of programmed cell death | defense response to other organism | regulation of immune system process | response to hormone | negative regulation of cellular process | negative regulation of leukocyte cell-cell adhesion | positive regulation of developmental process | negative regulation of RNA biosynthetic process | positive regulation of lymphocyte activation | regulation of T cell differentiation | defense response | lymphocyte costimulation | positive regulation of DNA recombination | positive regulation of cell adhesion | negative regulation of protein secretion | positive regulation of cellular component movement | positive regulation of protein secretion | positive regulation of T cell differentiation | negative regulation of T-helper 1 cell differentiation | positive regulation of CD4-positive, alpha-beta T cell costimulation | sterol metabolic process | regulation of immunoglobulin secretion | cellular process | regulation of cell motility | negative regulation of signaling | positive regulation of immune effector process | positive regulation of memory T cell differentiation | positive regulation of adaptive immune response | negative regulation of nucleic acid-templated transcription | negative regulation of alpha-beta T cell differentiation | negative regulation of apoptotic process | negative regulation of secretion | CD4-positive, alpha-beta T cell costimulation | positive regulation of nitrogen compound metabolic process | response to inorganic substance | negative regulation of establishment of protein localization | negative regulation of cellular metabolic process | regulation of cell differentiation | negative regulation of CD4-positive, alpha-beta T cell activation | response to prostaglandin | regulation of lymphocyte apoptotic process | negative regulation of apoptotic signaling pathway | regulation of immune response | regulation of cellular process | leukocyte activation | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | cellular response to prostaglandin stimulus | negative regulation of cytokine secretion | positive regulation of activated T cell proliferation | cellular response to molecule of bacterial origin | positive regulation of interferon-gamma production | organic cyclic compound metabolic process | positive regulation of T cell costimulation | regulation of type 2 immune response | positive regulation of T cell cytokine production | positive regulation of interleukin-4 production | T cell activation | regulation of peptide secretion | response to stimulus | negative regulation of protein transport | vasculature development | regulation of DNA recombination | regulation of regulatory T cell differentiation | negative regulation of T cell apoptotic process | chemokine (C-C motif) ligand 11 production | positive regulation of immune system process | negative regulation of cell adhesion | regulation of CD4-positive, alpha-beta T cell activation | mononuclear cell proliferation | positive regulation of immunoglobulin production | response to stress | negative regulation of lymphocyte activation | positive regulation of lymphocyte proliferation | positive regulation of T cell migration | alcohol metabolic process | regulation of cell proliferation | negative regulation of interferon-gamma production | positive regulation of T-helper 2 cell activation | positive regulation of cell-cell adhesion | positive regulation of cell activation | cellular response to inorganic substance | response to alcohol | cardiovascular system development | response to molecule of bacterial origin | positive regulation of T cell activation | negative regulation of transport | regulation of protein transport | negative regulation of metabolic process | negative regulation of hemopoiesis | regulation of peptide transport | regulation of cell adhesion | molecular function regulator | regulation of lymphocyte differentiation | blood vessel development | negative regulation of adaptive immune response | regulation of nucleic acid-templated transcription | positive regulation of peptide secretion | organic hydroxy compound metabolic process | response to nitrogen compound | cellular response to hormone stimulus | positive regulation of mononuclear cell proliferation | response to external biotic stimulus | system development | regulation of interleukin-4 production | regulation of signal transduction | negative regulation of secretion by cell | negative regulation of T-helper cell differentiation | multicellular organism development | positive regulation of lymphocyte differentiation | positive regulation of inflammatory response | response to fatty acid | lipid metabolic process | positive regulation of isotype switching to IgE isotypes | regulation of CD4-positive, alpha-beta T cell differentiation | positive regulation of lymphocyte migration | negative regulation of activation-induced cell death of T cells | regulation of T cell activation | cellular response to prostaglandin E stimulus | positive regulation of alpha-beta T cell differentiation | regulation of activated T cell proliferation | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | response to prostaglandin E | positive regulation of secretion | response to ketone | response to lipid | negative regulation of cytokine production | positive regulation of cellular metabolic process | positive regulation of alpha-beta T cell proliferation | regulation of lymphocyte activation | negative regulation of lymphocyte apoptotic process | regulation of nitrogen compound metabolic process | negative regulation of T cell activation | regulation of cell migration | small molecule metabolic process | positive regulation of interleukin-12 production | negative regulation of DNA-binding transcription factor activity | positive regulation of T-helper 2 cell differentiation | regulation of cellular component movement | positive regulation of interleukin-13 production | negative regulation of interleukin-17 production | memory T cell activation | positive regulation of cell differentiation | regulation of T cell cytokine production | negative regulation of extrinsic apoptotic signaling pathway | positive regulation of cell migration | cell proliferation | leukocyte proliferation | negative regulation of T-helper 1 type immune response | positive regulation of immunoglobulin mediated immune response | positive regulation of T cell proliferation | negative regulation of immune response | T-helper 2 cell activation | defense response to nematode | regulation of apoptotic signaling pathway | positive regulation of isotype switching | regulation of leukocyte migration | response to bacterium | negative regulation of cell-cell adhesion | regulation of cellular metabolic process | regulation of alpha-beta T cell differentiation | negative regulation of cell activation | regulation of T cell apoptotic process | regulation of T cell migration | inflammatory response | regulation of cytokine production involved in immune response | positive regulation of cell proliferation | positive regulation of establishment of protein localization | negative regulation of CD4-positive, alpha-beta T cell differentiation | regulation of locomotion | regulation of RNA metabolic process | positive regulation of interleukin-4-dependent isotype switching to IgE isotypes | positive regulation of B cell activation | positive regulation of transport | cellular response to fatty acid | negative regulation of T cell differentiation | lymphocyte activation | response to nitrogen dioxide | regulation of cytokine secretion | cytokine production | regulation of signaling receptor activity | receptor regulator activity | regulation of establishment of protein localization | positive regulation of type 2 immune response | positive regulation of T-helper cell differentiation | response to organic substance | regulation of hemopoiesis | chemokine production | regulation of DNA-binding transcription factor activity | anatomical structure development | metabolic process | regulation of isotype switching | regulation of adaptive immune response | regulation of RNA biosynthetic process | positive regulation of leukocyte activation | cholesterol metabolic process | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | positive regulation of cytokine production involved in immune response | positive regulation of memory T cell activation | regulation of secretion | receptor ligand activity | positive regulation of interleukin-6 production | immune response | cytokine activity | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | T cell proliferation | regulation of cell activation | regulation of protein secretion | positive regulation of leukocyte migration | alpha-beta T cell activation | positive regulation of cytokine production | cell activation | positive regulation of T cell mediated immunity | positive regulation of protein transport | regulation of T-helper cell differentiation | steroid metabolic process | T cell costimulation | lymphocyte proliferation | regulation of cell communication | positive regulation of interleukin-10 production | regulation of T-helper 1 cell differentiation | negative regulation of molecular function | negative regulation of signal transduction | regulation of immunoglobulin production | regulation of transcription, DNA-templated | regulation of T cell proliferation | positive regulation of CD4-positive, alpha-beta T cell differentiation | negative regulation of leukocyte apoptotic process | regulation of cytokine production | response to biotic stimulus | regulation of developmental process | positive regulation of DNA metabolic process | positive regulation of immunoglobulin secretion | developmental process | positive regulation of alpha-beta T cell activation | negative regulation of alpha-beta T cell activation | positive regulation of interleukin-2 production | regulation of transport | regulation of cell-cell adhesion | regulation of activation-induced cell death of T cells | innate immune response | positive regulation of metabolic process | acute inflammatory response | regulation of interferon-gamma production | immune system process | cellular response to organic substance | regulation of protein localization | regulation of cell death | positive regulation of cell motility | positive regulation of CD4-positive, alpha-beta T cell activation | negative regulation of cell death | regulation of interleukin-6 production | circulatory system development | regulation of inflammatory response | positive regulation of leukocyte cell-cell adhesion | regulation of lymphocyte migration | negative regulation of cell differentiation | regulation of memory T cell differentiation | response to other organism | regulation of signaling | negative regulation of regulatory T cell differentiation | cellular response to lipopolysaccharide | multicellular organismal process

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | extracellular region | extracellular space | cell surface | membrane