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QuickView for UCP;jsessionid=4DE4B75550CD33154135A82AC938EBE1;jsessionid=ECF4BCA078632217BD5B7FFDAD6C5E89 (gene)


Gene Symbol:
Ucp1 Rattus norvegicus Rattus norvegicus
Full name:
uncoupling protein 1
Synonyms:
Ucp, Ucpa, Uncp, mitochondrial brown fat uncoupling protein 1, UCP 1, solute carrier family 25 member 7, thermogenin, uncoupling protein 1 (mitochondrial, proton carrier)
Genomic Location:
Chr 19: 26527548-26535621
Description:
plays a role in heat production by uncoupling oxidative phosphorylation from the respiratory chain
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Bos taurus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene


Transcripts Names
NM_012682
Protein Names
P04633



GO Molecular Function

fatty acid binding | GDP binding | guanyl ribonucleotide binding | ribonucleoside binding | long-chain fatty acid binding | carboxylic acid binding | ribonucleotide binding | transmembrane transporter activity | lipid binding | nucleotide binding | carbohydrate derivative binding | phospholipid binding | phosphatidylglycerol binding | anion binding | purine nucleotide binding | transporter activity | ion binding | organic cyclic compound binding | purine nucleoside binding | purine ribonucleoside triphosphate binding | oxidative phosphorylation uncoupler activity | GTP binding | nucleoside binding | purine ribonucleotide binding | cardiolipin binding | organic acid binding | heterocyclic compound binding | guanyl nucleotide binding | small molecule binding

GO Biological Process

response to extracellular stimulus | response to nutrient levels | establishment of localization | response to hormone | cell differentiation | generation of precursor metabolites and energy | adaptive thermogenesis | cellular process | proton transmembrane transport | localization | diet induced thermogenesis | brown fat cell differentiation | regulation of cellular process | cellular response to lipid | regulation of metabolic process | transmembrane transporter activity | response to dehydroepiandrosterone | response to stimulus | response to cold | response to stress | response to alcohol | response to temperature stimulus | cellular response to organic cyclic compound | regulation of nucleic acid-templated transcription | cellular response to hormone stimulus | response to fatty acid | cellular response to oxidative stress | ion transmembrane transport | regulation of gene expression | response to ketone | cellular response to stress | response to lipid | cellular response to dehydroepiandrosterone | monovalent inorganic cation transport | mitochondrial transport | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | fat cell differentiation | response to oxidative stress | regulation of cellular metabolic process | regulation of RNA metabolic process | cellular response to fatty acid | oxidative phosphorylation uncoupler activity | cation transmembrane transport | response to organic substance | metabolic process | regulation of RNA biosynthetic process | mitochondrial transmembrane transport | cellular response to reactive oxygen species | response to reactive oxygen species | inorganic cation transmembrane transport | regulation of reactive oxygen species biosynthetic process | transmembrane transport | regulation of transcription, DNA-templated | response to organic cyclic compound | cation transport | developmental process | regulation of reactive oxygen species metabolic process | response to dietary excess | positive regulation of metabolic process | ion transport | cellular metabolic process | cellular response to organic substance | multicellular organismal process

GO Cellular Component

organelle inner membrane | intracellular membrane-bounded organelle | mitochondrial inner membrane | organelle membrane | cell | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | mitochondrial envelope | mitochondrial membrane | intracellular | membrane