QuickView for USP7;jsessionid=075D2A6408E87ECD830E22248BFDB116;jsessionid=5AA1F1BFD86E8476B5379EFE71158B91 (gene)
- Gene Symbol:
- Usp7
Rattus norvegicus - Full name:
- ubiquitin specific peptidase 7
- Synonyms:
- Hausp, ubiquitin carboxyl-terminal hydrolase 7, deubiquitinating enzyme 7, herpes-virus-associated ubiquitin-specific protease, herpesvirus-associated ubiquitin-specific protease, rHAUSP, ubiquitin specific peptidase 7 (herpes virus-associated), ubiquitin specific protease 7 (herpes virus-associated), ubiquitin thioesterase 7, ubiquitin-specific-processing protease 7
- Genomic Location:
- Chr 10: 6917612-6963452
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
Lys48-specific deubiquitinase activity | enzyme binding | thiol-dependent ubiquitinyl hydrolase activity | hydrolase activity | cysteine-type peptidase activity | catalytic activity | ubiquitin-like protein ligase binding | p53 binding | identical protein binding | thiol-dependent ubiquitin-specific protease activity | cysteine-type endopeptidase activity | protein binding | protein homodimerization activity | ubiquitinyl hydrolase activity | transcription factor binding | ubiquitin protein ligase binding | protein dimerization activity | endopeptidase activity | peptidase activity | protein C-terminus binding
GO Biological Process
protein modification by small protein removal | positive regulation of apoptotic process | proteolysis | protein stabilization | regulation of programmed cell death | negative regulation of cellular process | histone modification | negative regulation of proteolysis | cellular process | organic substance catabolic process | negative regulation of ubiquitin-dependent protein catabolic process | proteolysis involved in cellular protein catabolic process | chromatin organization | regulation of proteolysis | Lys48-specific deubiquitinase activity | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | protein deubiquitination | thiol-dependent ubiquitinyl hydrolase activity | negative regulation of cellular protein catabolic process | response to stimulus | regulation of cellular protein catabolic process | response to stress | cellular protein catabolic process | cellular nitrogen compound metabolic process | protein K48-linked deubiquitination | negative regulation of metabolic process | protein modification process | macromolecule modification | cysteine-type peptidase activity | DNA repair | regulation of nucleic acid-templated transcription | negative regulation of NF-kappaB transcription factor activity | nitrogen compound metabolic process | regulation of protein stability | multicellular organism development | cellular response to DNA damage stimulus | negative regulation of proteasomal ubiquitin-dependent protein catabolic process | regulation of gene expression | cellular response to stress | protein catabolic process | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | negative regulation of DNA-binding transcription factor activity | regulation of cellular protein metabolic process | positive regulation of DNA demethylation | thiol-dependent ubiquitin-specific protease activity | regulation of cellular metabolic process | regulation of protein metabolic process | cysteine-type endopeptidase activity | regulation of RNA metabolic process | regulation of proteasomal ubiquitin-dependent protein catabolic process | protein metabolic process | DNA metabolic process | histone H2B conserved C-terminal lysine deubiquitination | regulation of DNA-binding transcription factor activity | cellular macromolecule catabolic process | anatomical structure development | metabolic process | nucleotide-excision repair | regulation of protein catabolic process | regulation of RNA biosynthetic process | regulation of proteasomal protein catabolic process | positive regulation of cell death | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of cellular protein metabolic process | positive regulation of programmed cell death | protein modification by small protein conjugation or removal | maintenance of DNA methylation | ubiquitin-dependent protein catabolic process | negative regulation of protein catabolic process | negative regulation of protein metabolic process | organonitrogen compound catabolic process | transcription-coupled nucleotide-excision repair | negative regulation of molecular function | covalent chromatin modification | regulation of transcription, DNA-templated | endopeptidase activity | cellular protein metabolic process | positive regulation of DNA metabolic process | developmental process | organelle organization | cellular protein modification process | heterocycle metabolic process | positive regulation of metabolic process | chromosome organization | cellular metabolic process | peptidase activity | regulation of cell death | modification-dependent protein catabolic process | histone deubiquitination | regulation of ubiquitin-dependent protein catabolic process | negative regulation of proteolysis involved in cellular protein catabolic process | monoubiquitinated protein deubiquitination | macromolecule metabolic process | multicellular organismal process | negative regulation of proteasomal protein catabolic process
GO Cellular Component
chromosome | intracellular membrane-bounded organelle | cell | nuclear lumen | sex chromosome | cytoplasm | intracellular organelle | nuclear body | protein-containing complex | PML body | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | XY body | cytosol | intracellular
