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QuickView for paralyzed;jsessionid=D921D3EE17914A42C45A0415C3311C42;jsessionid=E415AB5B8CF0B418C2CE21F3CD2A98B0 (gene)


Gene Symbol:
Scn3a Rattus norvegicus Rattus norvegicus
Full name:
sodium voltage-gated channel alpha subunit 3
Synonyms:
Nav1.3, SCIII, Scn2a, sodium channel protein type 3 subunit alpha, rCG26412-like, sodium channel protein type 3 subunit alpha-like, sodium channel protein type III subunit alpha, sodium channel protein, brain III subunit alpha, sodium channel, voltage-gated, type 3, alpha subunit, sodium channel, voltage-gated, type III, alpha subunit, voltage-gated sodium channel subtype III, voltage-gated sodium channel subunit alpha Nav1.3
Genomic Location:
Chr 3: 47421321-47543606
Description:
may play a role in neuronal hyperexcitability and neuropathic pain in response to spinal cord injury
Orthologs:
Homo sapiens Mus musculus D. melanogaster Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
miRNA binding sites
(Source: miRecords):





GO Molecular Function

voltage-gated ion channel activity | cation binding | passive transmembrane transporter activity | voltage-gated sodium channel activity | transmembrane transporter activity | ion gated channel activity | cation transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | ion binding | protein binding | metal ion transmembrane transporter activity | sodium ion transmembrane transporter activity | sodium channel activity | cation channel activity | sodium ion binding | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | voltage-gated channel activity | channel activity | calmodulin binding | metal ion binding | ion channel activity | substrate-specific channel activity

GO Biological Process

regulation of localization | establishment of localization | nervous system development | membrane depolarization during action potential | voltage-gated ion channel activity | response to antibiotic | response to pyrethroid | cellular process | localization | passive transmembrane transporter activity | metal ion transport | voltage-gated sodium channel activity | transmembrane transporter activity | response to stimulus | ion gated channel activity | response to stress | neuronal action potential | regulation of membrane potential | system development | cellular response to antibiotic | multicellular organism development | ion transmembrane transport | nervous system process | sodium ion transport | cation transmembrane transporter activity | monovalent inorganic cation transport | ion transmembrane transporter activity | sensory perception of pain | response to toxic substance | cell communication | response to insecticide | cation transmembrane transport | response to wounding | metal ion transmembrane transporter activity | anatomical structure development | membrane depolarization | sodium ion transmembrane transport | sodium ion transmembrane transporter activity | inorganic cation transmembrane transport | regulation of ion transmembrane transport | sodium channel activity | cation channel activity | sensory perception | transmembrane transport | action potential | signaling | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | voltage-gated channel activity | cation transport | channel activity | regulation of ion transport | developmental process | regulation of transport | transmission of nerve impulse | ion channel activity | ion transport | substrate-specific channel activity | multicellular organismal process

GO Cellular Component

integral component of membrane | voltage-gated sodium channel complex | neuron projection | somatodendritic compartment | cell body | cell | neuronal cell body | plasma membrane protein complex | intrinsic component of membrane | cytoplasm | protein-containing complex | cell projection | plasma membrane | integral component of plasma membrane | sodium channel complex | cell periphery | axon | transmembrane transporter complex | cation channel complex | ion channel complex | intracellular | membrane | intrinsic component of plasma membrane