QuickView for spastin;jsessionid=35B104413BB1A6BFDF0405A4F5750D69;jsessionid=6A5B0060C9CCB7438E6F9FCA58D1772D;jsessionid=A9EA8F33787D13705D13FFEB69D527F9;jsessionid=72CBA7F19EC45CEB81CB69B863D48DF9 (gene)
- Gene Symbol:
- spast
Danio rerio - Full name:
- spastin
- Synonyms:
- CH73-233A22.3, MGC85952, zgc:85952
- Genomic Location:
- Chr 1: 49266465-49283984
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Gallus gallus , Pan troglodytes , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
alpha-tubulin binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | beta-tubulin binding | ATP binding | cytoskeletal protein binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | hydrolase activity, acting on acid anhydrides | microtubule binding | microtubule-severing ATPase activity | purine ribonucleotide binding | tubulin binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding
GO Biological Process
mitotic cytokinesis | regulation of supramolecular fiber organization | protein homooligomerization | cell morphogenesis | nucleus organization | protein hexamerization | microtubule-based transport | microtubule cytoskeleton organization involved in mitosis | regulation of microtubule polymerization or depolymerization | positive regulation of cellular component organization | regulation of cell morphogenesis | regulation of neurogenesis | neuron projection morphogenesis | regulation of cell development | microtubule bundle formation | regulation of programmed cell death | establishment of localization | negative regulation of cellular process | positive regulation of developmental process | microtubule cytoskeleton organization | cell differentiation | nervous system development | reactive oxygen species metabolic process | cell part morphogenesis | positive regulation of axonogenesis | neurogenesis | regulation of organelle organization | generation of neurons | membrane organization | intracellular transport | microtubule-based process | neuron projection extension | cellular process | establishment of organelle localization | central nervous system neuron axonogenesis | localization | cell projection morphogenesis | developmental growth | neuron development | central nervous system neuron differentiation | synapse assembly | cytoskeleton-dependent cytokinesis | negative regulation of apoptotic process | endomembrane system organization | regulation of neuron projection development | establishment of localization in cell | regulation of cell differentiation | cytoskeleton-dependent intracellular transport | regulation of cellular process | positive regulation of cell growth | regulation of apoptotic process | organelle localization | positive regulation of protein complex disassembly | cellular component organization | regulation of microtubule depolymerization | cell morphogenesis involved in neuron differentiation | nuclear envelope reassembly | mitotic spindle organization | organelle transport along microtubule | supramolecular fiber organization | exit from mitosis | microtubule-based movement | cellular localization | nuclear envelope organization | regulation of cellular component size | cellular component assembly | regulation of axon extension | mitochondrion transport along microtubule | central nervous system neuron development | system development | positive regulation of organelle organization | positive regulation of neuron projection development | multicellular organism development | regulation of axonogenesis | protein complex oligomerization | regulation of protein complex disassembly | regulation of neuron differentiation | axon development | cell cycle | membrane fission | positive regulation of cell projection organization | positive regulation of protein depolymerization | synapse organization | axonogenesis | positive regulation of cell differentiation | mitochondrion localization | cell division | cytokinesis | mitotic cell cycle phase transition | cell morphogenesis involved in differentiation | anterograde axonal transport | cytoplasmic microtubule organization | positive regulation of cytoskeleton organization | regulation of protein depolymerization | microtubule severing | regulation of microtubule-based process | organelle disassembly | positive regulation of axon extension | neuron differentiation | protein-containing complex assembly | regulation of cell morphogenesis involved in differentiation | regulation of growth | establishment of mitochondrion localization, microtubule-mediated | axon extension | establishment of mitochondrion localization | anatomical structure development | developmental growth involved in morphogenesis | mitotic cell cycle | positive regulation of neurogenesis | nuclear division | cell projection organization | metabolic process | positive regulation of cell development | positive regulation of supramolecular fiber organization | negative regulation of programmed cell death | transport along microtubule | neuron projection development | cytoskeleton organization | mitotic nuclear division | vesicle organization | microtubule-severing ATPase activity | axo-dendritic transport | positive regulation of developmental growth | positive regulation of growth | cell development | regulation of developmental growth | regulation of cell size | anatomical structure morphogenesis | endosome organization | regulation of nervous system development | regulation of developmental process | developmental process | axonal transport of mitochondrion | organelle organization | regulation of cell growth | developmental cell growth | cell cycle phase transition | positive regulation of microtubule depolymerization | central nervous system development | positive regulation of neuron differentiation | regulation of cell projection organization | cellular metabolic process | regulation of cell death | positive regulation of cell morphogenesis involved in differentiation | negative regulation of cell death | spindle organization | regulation of microtubule cytoskeleton organization | regulation of cellular component organization | axonal transport | mitotic spindle disassembly | regulation of cytoskeleton organization | multicellular organismal process
GO Cellular Component
supramolecular fiber | intracellular membrane-bounded organelle | organelle membrane | microtubule organizing center | nuclear membrane | cell | microtubule | cytoplasm | intracellular organelle | endomembrane system | nuclear envelope | midbody | perinuclear region of cytoplasm | microtubule cytoskeleton | membrane-bounded organelle | nucleus | organelle | cytoskeleton | intracellular | membrane | supramolecular complex
