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QuickView for 5,6,7,8-tetrahydrobiopterin (compound)


Genetic Markers

Most Correlated Genes

  1. TH
  2. NOS3
  3. PAH
  4. TPH1
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Pathway Enrichment

Most Correlated Biogroups

  1. Aromatic amino acid monoxygenase, C-terminal domain superfamily
  2. Aromatic amino acid hydroxylase, iron/copper binding site
  3. Aromatic amino acid hydroxylase superfamily
  4. Aromatic amino acid hydroxylase
  5. Aromatic amino acid hydroxylase, C-terminal
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Curated Studies

Most Correlated Studies

  1. Drug target sets for approved compounds
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Literature

Most Relevant Literature

  1. Tetrahydrobiopterin and Its Multiple Roles in Neuropsychological Disorders.
  2. Impact on Diet Quality and Burden of Care in Sapropterin Dihydrochloride Use in Children with Phenyl…
  3. Tetrahydrobiopterin in Cell Function and Death Mechanisms.
  4. Metronidazole, acyclovir and tetrahydrobiopterin may be promising to treat COVID-19 patients, throug…
  5. Disruption of tetrahydrobiopterin (BH4) biosynthesis pathway affects cuticle pigmentation in Henosep…
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Clinical Trials

Most Relevant Clinical Trials

  1. Effects of Tetrahydrobiopterin on Blood Pressure
  2. Tetrahydrobiopterin in Patients With Chronic Kidney Disease (CKD) and Albuminuria
  3. A Study for Assessing the Efficacy and Safety of Tetrahydrobiopterin in Radiation-Induced Skin Injur…
  4. A Study of CNSA-001 in Primary Tetrahydrobiopterin (BH4) Deficient Participants With Hyperphenylalan…
  5. Tetrahydrobiopterin Treatment in Children With Idiopathic Cognitive Developmental Disorders
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