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NrF2 protein
(compound)
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Genetic Markers
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No genes found
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Pathway Enrichment
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Curated Studies
Most Correlated Studies
Skin expressing homozygous and heterozygous constitutively active NRF2
Whole skins from mutant NRF2 expressing transgenic mice
Lungs from NRF2 knockout mice exposed to R-sulforaphane followed by hyperoxia
Livers of mice with Nfe2l2 (Nrf2) knockout, Keap1 hepatocyte-specific knockout, or Keap1 knockdown
Hepatocellular carcinoma HepG2 cells, a model of drug induced liver injury
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Literature
Most Relevant Literature
UBXN7 cofactor of CRL3KEAP1 and CRL2VHL ubiquitin ligase complexes mediates reciprocal regulation of…
Attenuation of LPS-induced acute lung injury by continentalic acid in rodents through inhibition of …
PAQR4 promotes chemoresistance in non-small cell lung cancer through inhibiting Nrf2 protein degrada…
C60 Fullerene Reduces 3-Nitropropionic Acid-Induced Oxidative Stress Disorders and Mitochondrial Dys…
Dr. Jekyll and Mr. Hyde: Oxidizable phenol-generated reactive oxygen species enhance sulforaphane's …
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Clinical Trials
Most Relevant Clinical Trials
Treatment Strategy to Enhance Nrf2 Signaling in Older Adults
Broccoli Sprout Extracts Trial to See if NRF2 is Enhanced by Sulforaphane Treatment in Patients With…
Characterization of the Nrf2 Response in Patients With Autosomal Dominant Polycystic Kidney Disease …
Effects of Physical Activities on the Expression of Nrf2 and Nf-kb Hemodialysis Patients
Pyrimethamine as an Inhibitor of NRF2 in HPV-negative Locally Advanced Head and Neck Squamous Cell C…
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