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PROTACS
Summary
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Curated Studies
Most Correlated Studies
Secondary AML cells treated with ARV-825, a BET-domain proteolysis-targeting chimera (BET-PROTAC)
Non-Hodgkin lymphoma Mino cells treated with ARV-771, ARV-825 or OTX015
AML MOLM-16 cells and ALCL SU-DHL-1 cells treated with SD-36 or inactive control SD-36Me
Prostate carcinoma 22Rv1 cells resistant to JQ1
Prostate cancer cells treated with SMARCA2/4 degrader AU-15330 and BRD4 degrader ZBC-260
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Literature
Most Relevant Literature
Non-small molecule PROTACs (NSM-PROTACs): Protein degradation kaleidoscope.
Stimuli-Responsive PROTACs for Controlled Protein Degradation.
Antiviral PROTACs: Opportunity borne with challenge.
Design, synthesis and biological evaluation of KRASG12C-PROTACs.
Self-Assembled Nano-PROTAC Enables Near-Infrared Photodynamic Proteolysis for Cancer Therapy.
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Clinical Trials
Most Relevant Clinical Trials
Effects of Systematic Proprioceptive-tactile Stimulation With Use of the Protac MyFit®
Ball Blankets on Insomnia in Depression in Outpatient Clinics
A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With The Physici…
Study of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to HR+/HER2- Breast Cance…
TACTIVE-U: A Study to Learn About the Study Medicine (Called ARV-471) When Given With Other Medicine…
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