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QuickView for Shiga toxins (compound)


Genetic Markers

Most Correlated Genes

  1. CXCL8
  2. ATF3
  3. ACKR3
  4. GDF15
  5. PMAIP1
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Pathway Enrichment

Most Correlated Biogroups

  1. BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
  2. LEE_BMP2_TARGETS_DN
  3. HALLMARK_TNFA_SIGNALING_VIA_NFKB
  4. WEI_MYCN_TARGETS_WITH_E_BOX
  5. NAGASHIMA_NRG1_SIGNALING_UP
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Curated Studies

Most Correlated Studies

  1. Microvascular endothelial cells response to Shiga toxins
  2. Shiga toxin-induced gene expression in THP-1 monocytic leukemia cells
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Literature

Most Relevant Literature

  1. Complex effects of the exo-xis region of the Shiga toxin-converting bacteriophage Φ24B genome on the…
  2. The Fatal Role of Enterohaemorrhagic Escherichia coli Shiga Toxin-associated Extracellular Vesicles …
  3. Prevalence and molecular characterization of shiga toxin-producing Escherichia coli in animal source…
  4. Volume expansion mitigates Shiga toxin-producing E. coli-hemolytic uremic syndrome in children.
  5. High diversity in the regulatory region of Shiga toxin encoding bacteriophages.
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Clinical Trials

Most Relevant Clinical Trials

  1. Study of Chimeric Monoclonal Antibodies to Shiga Toxins 1 and 2
  2. Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection
  3. Shiga Toxin Producing Escherichia Coli (STEC) Volume Expansion
  4. Eculizumab in Shiga-toxin Related Hemolytic and Uremic Syndrome Pediatric Patients - ECULISHU
  5. Safety and Efficacy Study of Eculizumab in Shiga-Toxin Producing Escherichia Coli Hemolytic-Uremic S…
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