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QuickView for TP53 (gene)


Body Atlas

Most Correlated Tissues

  1. B lymphocyte (IgM memory) of spleen
  2. Granulocyte-macrophage progenitor cell of bone marrow
  3. Nipple cross-section
  4. Tonsil
  5. Endometrium
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Disease Atlas

Most Correlated Diseases

  1. Neurocutaneous syndrome
  2. Disorder of intraocular pressure
  3. Parvovirus infection
  4. Chondrodysplasia
  5. Polyp of intestine
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Pharmaco Atlas

Most Correlated Compounds

  1. P2 protein, Sulfolobus
  2. AS 1411
  3. Seminal Plasma Proteins
  4. MART-1 Antigen
  5. Colcemide
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. MIR424
  2. SART3
  3. EIF5A
  4. CDKN1A
  5. DMRT1
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. TP53: the unluckiest of genes?
  2. Dissociating the metabolic and tumor-suppressive activity of p53.
  3. TP53 mutations in cancer: Molecular features and therapeutic opportunities (Review).
  4. 53BP1-mediated activation of the tumor suppressor p53.
  5. Deciphering the significance of p53 mutant proteins.
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Clinical Trials

Most Relevant Clinical Trials

  1. Li-Fraumeni Syndrome/TP53 Biobank
  2. Li-Fraumeni & TP53 (LiFT UP)
  3. Biomarker Monitoring in TP53 Mutation Carriers
  4. The Role of Hypoxia as a Selective Pressure for TP53 Mutations
  5. Advanced Refractory Solid Tumors With TP53 Mutations Register Study
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