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interleukin 23
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
GZMB
IL2
CCL20
TNFSF14
S100A8
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Pathway Enrichment
Most Correlated Biogroups
PUJANA_BRCA1_PCC_NETWORK
PUJANA_CHEK2_PCC_NETWORK
LEE_BMP2_TARGETS_DN
DODD_NASOPHARYNGEAL_CARCINOMA_DN
BERENJENO_TRANSFORMED_BY_RHOA_UP
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Curated Studies
Most Correlated Studies
Expression data for effector T cells
CD4+ T cells activated and differentiated with Th17-inducing cytokine combinations
Th17 cells deficient for Sgk1 and treated with IL23
CD4+ T cells differentiation into Th17 cells in the presence of TGF-beta1 and IL-6
Innate lymphoid cells (ILCs) stimulated with cytokines and/or NKp44 antibody
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Literature
Most Relevant Literature
Targeting IL-23 for IBD: Rationale and Progress to Date.
IL-12 and IL-23 pathway inhibition in inflammatory bowel disease.
Efficacy and safety of IL-23 inhibitors in the treatment of psoriatic arthritis: a meta-analysis bas…
A review of JAK and IL-23 inhibitors to treat vitiligo.
Blockade of IL-23: What is in the Pipeline?
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Clinical Trials
Most Relevant Clinical Trials
Low-dose Interleukin-2 in Combination With Standard Therapy on Idiopathic Inflammatory Myopathy
The Effect of Acupuncture on the Treatment of Endovenous Ablation on Pain, IL17 and IL 23
Rituximab and Interleukin-12 in Treating Patients With B-Cell Non-Hodgkin's Lymphoma
The Role of IL-23 in Chronic Inflammatory Disease: Exploring the Cellular and Molecular Targets of I…
Low-dose Interleukin-2 and Pembrolizumab in Melanoma and Renal Cell Cancer
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