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prion disease
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Summary
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Genetic Markers
Most Correlated Genes
Most Correlated SNPs
PRNP
GPSC
HLA-DQB1
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Pathway Enrichment
Most Correlated Biogroups
GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_UP
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP
response to organic substance
LEE_AGING_CEREBELLUM_UP
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Curated Studies
Most Correlated Studies
Breast cancer and malignant melanoma cell lines compared with non-tumorigenic cell lines
Myoblast C2C12 cells differentiated into myotubes and infected with prions
Thalami and parietal lobes of patients with fatal familial insomnia
Brains of mice with Creutzfeldt-Jakob disease or fatal familial insomnia - PRNP associated RNA
Mouse Phenotypes - Canavan's disease
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Literature
Most Relevant Literature
Cellular toxicity of scrapie prions in prion diseases; a biochemical and molecular overview.
Human prion diseases: An overview].
Hypothesis: functional age and onset of autosomal dominant genetic prion disease.
Non-human primates in prion diseases.
Genetic prion diseases presenting as frontotemporal dementia: clinical features and diagnostic chall…
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Clinical Trials
Most Relevant Clinical Trials
PRION-1: Quinacrine for Human Prion Disease
Biomarker Profiling in Individuals at Risk for Prion Disease
The Role of the Coagulation Pathway at the Synapse in Prion Diseases
Enhanced CJD Surveillance in the Older Population
Nilotinib in Huntington's Disease
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