QuickView for 53BP1;jsessionid=99B8E7102C9C302A519337C3600B16CF;jsessionid=D492AD8AFA60F602FE2D2498AEF5F9A9;jsessionid=58A9B6B6A6CCF36EA3BA2C61FA917C5D (gene)

Summary
General Info

Body Atlas

Most Correlated Tissues

Pituitary gland
Cerebellum
Cerebellar hemisphere
Hypothalamus
Superior cervical ganglion

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Disease Atlas

Most Correlated Diseases

Poisoning by drug AND/OR medicinal substance
Bacterial infectious disease
Toxic nephropathy
Caseating tuberculoid granuloma
11p partial monosomy syndrome

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Pharmaco Atlas

Most Correlated Compounds

alphaxalone
Aminoglutethimide
Metyrapone
Trimethoprim
1,5-naphthalenediamine

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Knockdown Atlas

Most Correlated Gene Perturbations

Jak2
SEC16A
TP53BP1
MIR122
AKR1A1

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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

Isorhamnetin Promotes 53BP1 Recruitment through the Enhancement of ATM Phosphorylation and Protects …
Centrosome defects cause microcephaly by activating the 53BP1-USP28-TP53 mitotic surveillance pathwa…
βarrestin-1 regulates DNA repair by acting as an E3-ubiquitin ligase adaptor for 53BP1.
miR‑7/SP1/TP53BP1 axis may play a pivotal role in NSCLC radiosensitivity.
53BP1 loss rescues embryonic lethality but not genomic instability of BRCA1 total knockout mice.

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Clinical Trials

Most Relevant Clinical Trials

There were no clinical trials for 53BP1;jsessionid=99B8E7102C9C302A519337C3600B16CF;jsessionid=D492AD8AFA60F602FE2D2498AEF5F9A9;jsessionid=58A9B6B6A6CCF36EA3BA2C61FA917C5D

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