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IRAK
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Summary
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Body Atlas
Most Correlated Tissues
Parotid gland
Natural killer cell of peripheral blood
Dendritic (plasmacytoid) cell
Microglial cell
Plasma cell of spleen
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Literature
Most Relevant Literature
IRAK1 and IRAK4 as emerging therapeutic targets in hematologic malignancies.
The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii inf…
Nonhematopoietic IRAK1 drives arthritis via neutrophil chemoattractants.
IRAK1 inhibition blocks the HIV-1 RNA mediated pro-inflammatory cytokine response from microglia.
Pacritinib Inhibition of IRAK1 Blocks Aberrant TLR8 Signalling by SARS-CoV-2 and HIV-1-Derived RNA.
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Clinical Trials
Most Relevant Clinical Trials
A Phase 1/2 Study of Oral IRAK-4 Inhibitor CA-4948 in Combination With Pembrolizumab Following Stere…
IRAK 4 Inhibitor (PF-06650833) in Hospitalized Patients With COVID-19 Pneumonia and Exuberant Inflam…
TLR Polymorphism, ASO and Beta-hemolytic Group A Streptococcus Infections in ADHD: an Observational …
Multicentric, Transversal, Descriptive, Epidemiological Study on the Management of Asthma in Asthmat…
Mathematical Modeling of the Acute Inflammatory Response Following Injury
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