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QuickView for MENIN (gene)


Body Atlas

Most Correlated Tissues

  1. Superior cervical ganglion
  2. Appendix
  3. Ascending colon
  4. Adrenal gland
  5. Fetal lung
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Disease Atlas

Most Correlated Diseases

  1. Disorder of parathyroid gland
  2. Pituitary gland cancer
  3. Parathyroid carcinoma
  4. Adrenal cancer
  5. Irritable bowel syndrome
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Pharmaco Atlas

Most Correlated Compounds

  1. Creatine
  2. Moclobemide
  3. Amodiaquine
  4. Iodipamide
  5. Nizatidine
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. BP1
  2. MIR218-1
  3. SHC2
  4. ZNF143
  5. BCL2A1
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Sarcomas arising in MEN1 patients: demonstrating LOH of the MEN1 locus and loss of menin expression.
  2. Hypothalamic Menin regulates systemic aging and cognitive decline.
  3. Menin signaling and therapeutic targeting in breast cancer.
  4. Menin orchestrates macrophage reprogramming to maintain the pulmonary immune homeostasis.
  5. Menin inhibitors in the treatment of acute myeloid leukemia.
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Clinical Trials

Most Relevant Clinical Trials

  1. Study of BMF-219, a Covalent Menin Inhibitor, in Adult Patients With AML, ALL (With KMT2A/ MLL1r, NP…
  2. Study of Covalent Menin Inhibitor BMF-219 in Adult Patients With KRAS Driven Non-Small Cell Lung Can…
  3. A Multi-Site Break Through Cancer Trial: Phase II Study Investigating Dual Inhibition of BCL2 and Me…
  4. A Phase II Study of the Menin Inhibitor Revumenib in Leukemia Associated With Upregulation of HOX Ge…
  5. A Study of Ziftomenib, an Oral Menin Inhibitor, in Combination with Imatinib in Patients with Advanc…
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