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QuickView for Sevenless


Curated Studies

Most Correlated Studies

  1. Eye imaginal discs with sevenless gain-of-function or loss-of-function alleles
  2. Keratinocyte specific Fos-deletion in K5-Sos-F mouse tumor model
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Literature

Most Relevant Literature

  1. Allosteric autoactivation of SOS and its kinetic mechanism.
  2. Interactions of the N- and C-Terminal SH3 Domains of Drosophila Drk with the Proline-Rich Peptides f…
  3. Relating cellular signaling timescales to single-molecule kinetics: A first-passage time analysis of…
  4. Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos.
  5. Development of Noonan syndrome by deregulation of allosteric SOS autoactivation.
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Clinical Trials

Most Relevant Clinical Trials

  1. A Study to Test Different Doses of BI 1701963 Alone and Combined With Trametinib in Patients With Di…
  2. A Study to Test Different Doses of BI 1701963 in Combination With Irinotecan in People With Advanced…
  3. A Study to Test Different Doses of BI 1823911 Alone and Combined With Other Medicines in People With…
  4. A Study to Find a Safe and Effective Dose of BI 1701963 Alone and in Combination With BI 3011441 in …
  5. A Study of VS-6766 and Cetuximab in Patients With Advanced Colorectal Cancer
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