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QuickView for Simvastatin (compound)


Genetic Markers

Most Correlated Genes

  1. EHHADH
  2. Acot1
  3. HMGCR
  4. PDK4
  5. NFE2
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Pathway Enrichment

Most Correlated Biogroups

  1. response to organic substance
  2. organic cyclic compound binding
  3. heterocyclic compound binding
  4. organic cyclic compound metabolic process
  5. enzyme binding
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Curated Studies

Most Correlated Studies

  1. Diverse liver drug signatures
  2. Genomics Assisted Toxicity Evaluation system study - Human Hepatocytes
  3. Genomics Assisted Toxicity Evaluation system study - Rat Liver Single Dose
  4. Genomics Assisted Toxicity Evaluation system study - Rat Liver Repeat Doses
  5. Genomics Assisted Toxicity Evaluation system study - Rat Hepatocytes
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Literature

Most Relevant Literature

  1. Effects of Simvastatin on Alveolar Regeneration and Its Relationship to Exposure in Mice with Dexame…
  2. Efficacy of simvastatin in reducing postoperative adhesions after thyroidectomy: an experimental stu…
  3. The impact of pretreatment with simvastatin on kidney tissue of rats with acute sepsis.
  4. The functional mechanism of simvastatin in experimental osteoporosis.
  5. Benefit of Ezetimibe Added to Simvastatin in Reduced Kidney Function.
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Clinical Trials

Most Relevant Clinical Trials

  1. The DDI Study of SP2086 and Simvastatin
  2. 7-day Simvastatin and Emotional Processing
  3. Sarilumab Effect on the Pharmacokinetics of Simvastatin
  4. Simvastatin in Chronic Obstructive Pulmonary Disease (COPD)
  5. Simvastatin for mTBI
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