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Tolbutamide
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
SLC16A6
ABCC8
NEAT1
AGR2
KIF20A
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Pathway Enrichment
Most Correlated Biogroups
organic cyclic compound binding
heterocyclic compound binding
organic cyclic compound metabolic process
FISCHER_DREAM_TARGETS
heterocycle metabolic process
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Curated Studies
Most Correlated Studies
Hepatocellular carcinoma HepG2 cells treated with hepatotoxic or non-hepatotoxic compounds
Hepatoma cells, hepatocellular carcinoma cells, and induced hepatocytes treated with carcinogens
Hepatocytes conventionally cultured or trichostatin A-stabilized treated with hepatocarcinogens
Genomics Assisted Toxicity Evaluation system study - Human Hepatocytes
Genomics Assisted Toxicity Evaluation system study - Rat Liver Single Dose
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Literature
Most Relevant Literature
Assessment of CYP2B6 activity in rats: a cocktail study with bupropion alone and in combined with to…
Studying significance of apoptosis in mediating tolbutamide-induced teratogenesis in vitro.
Evaluation of the pharmacokinetic interaction between ticagrelor and tolbutamide, a cytochrome P450 …
Synthesis and preliminary biological profile of new NO-donor tolbutamide analogues.
UPLC-MS-MS method for simultaneous determination of caffeine, tolbutamide, metoprolol, and dapsone i…
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Clinical Trials
Most Relevant Clinical Trials
Study to Evaluate the Effect of Multiple-Dose Ritlecitinib on the Pharmacokinetics (PK) of Tolbutami…
Effects of Genotype on CYP2C9 Drug Interactions
A Drug Interaction Study of Tasisulam in Patients With Advanced Cancer or Lymphoma
A Study to Assess Effect of JNJ-54861911 on Pharmacokinetics of Cocktail Representatives for Cytochr…
Drug Interaction Study of CT1812 in Healthy Volunteers
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