QuickView for XM_215254 (gene)

1. Human Smc5/6 recognises transcription-generated positive DNA supercoils.
2. Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms.
3. SMC5 Plays Independent Roles in Congenital Heart Disease and Neurodevelopmental Disability.
4. The SMC5/6 complex prevents genotoxicity upon APOBEC3A-mediated replication stress.
5. Crucial role of the NSE1 RING domain in Smc5/6 stability and FANCM-independent fork progression.

There were no clinical trials for XM_215254