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YAP1
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Body Atlas
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Curated Studies
Most Correlated Studies
MKN45 gastric cancer cells expressing constitutively active mutant YAP1
Hepatocellular carcinoma SK-HEP1 cells treated with HIPPO signaling pathway siRNA knockdowns
Colorectal cancer HCT 116 cells expressing KRAS shRNA and KRAS or YAP1 open reading frames
Pancreatic tumor KRASG12D induced, xenografts with YAP1 expression (KRASG12D off)
Hepatic adenocarcinoma cells SK-Hep1 with siRNA targeting YAP1 and TAZ
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Literature
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Long term exposure of saxitoxin induced cognitive deficits and YAP1 cytoplasmic retention.
The TGFβ→TAK1→LATS→YAP1 Pathway Regulates the Spatiotemporal Dynamics of YAP1.
YAP1 is essential for malignant mesothelioma tumor maintenance.
YAP1 suppression inhibits autophagy and improves the efficacy of anti-PD-1 immunotherapy in hepatoce…
The oncogenic role of NF1 in gallbladder cancer through regulation of YAP1 stability by direct inter…
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Clinical Trials
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Oral TEAD Inhibitor Targeting the Hippo Pathway in Subjects With Advanced Solid Tumors
Tissue Predictors of Abiraterone Benefit
Investigating Hereditary Risk In Thoracic Cancers (INHERIT)
A Study of ION537 in Patients With Molecularly Selected Advanced Solid Tumors
Testing a New Anti-cancer Drug Combination, Entinostat and GSK525762C, for Advanced and Refractory S…
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