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alpha 1 proteinase inhibitor
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
IGHM
CELA3B
Speer4cos
CES3
Gm1995
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Pathway Enrichment
Most Correlated Biogroups
PILON_KLF1_TARGETS_DN
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP
MILI_PSEUDOPODIA_HAPTOTAXIS_UP
JOHNSTONE_PARVB_TARGETS_3_DN
GOLDRATH_ANTIGEN_RESPONSE
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Curated Studies
Most Correlated Studies
Fat and pancreatic lymph nodes of NOD mice treated with Power Mix (PM) or alpha-1 antitrypsin (AAT)
L1000 CMAP - Colorectal cancer HT29 cells treated with ligand perturbagens
L1000 CMAP - Prostate carcinoma VCaP cells treated with ligand perturbagens
L1000 CMAP - Lung cancer A549 cells treated with ligand perturbagens
L1000 CMAP - Adenocarcinoma of breast MCF7 cells treated with ligand perturbagens
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Literature
Most Relevant Literature
Expert Perspectives on the Management of Alpha 1-Antitrypsin Deficiency.
Gene therapy for alpha-1 antitrypsin deficiency: an update.
Optimizing the screening of alpha-1 antitrypsin deficiency using serum protein electrophoresis.
Augmentation Therapy with Alpha-1 Antitrypsin: Present and Future of Production, Formulation, and De…
Estimated Worldwide Prevalence of the PI*ZZ Alpha-1 Antitrypsin Genotype in Subjects With Chronic Ob…
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Clinical Trials
Most Relevant Clinical Trials
Efficacy and Safety Study of Augmentation Therapy With ARALAST Fraction IV-1 (Human Alpha 1 - Protei…
Safety and Pharmacokinetics of Alpha-1 Proteinase Inhibitor in Subjects With Alpha1-Antitrypsin Defi…
Phase II/III Study of an Alpha-1 Proteinase Inhibitor (Kamada-API) in Individuals With Alpha-1 Antit…
Safety and Tolerability Trial of Inhaled Alpha1-Proteinase Inhibitor (Human), Hydrophobic Chromatogr…
Efficacy and Safety of Alpha1-Proteinase Inhibitor (Human), Modified Process (Alpha-1 MP) in Subject…
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