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QuickView for anticholesteremic agents (compound)


Genetic Markers

Most Correlated Genes

  1. Acot1
  2. PDK4
  3. EHHADH
  4. ACOT2
  5. HMGCR
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Pathway Enrichment

Most Correlated Biogroups

  1. response to organic substance
  2. organic cyclic compound metabolic process
  3. DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP
  4. heterocyclic compound binding
  5. PILON_KLF1_TARGETS_DN
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Curated Studies

Most Correlated Studies

  1. Genomics Assisted Toxicity Evaluation system study - Human Hepatocytes
  2. Cardiac gene expression regulated by single fatty acids in wildtype and PPARa null mice
  3. Testes expression profiles from ABDG8 KO and WT mice and ezetimibe treated ABDG8 KO mice
  4. Peripheral atherosclerosis plaques after simvastatin, losartan or pioglitazone treatment
  5. Hepatocytes treated with non-genotoxic carcinogens
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Literature

Most Relevant Literature

  1. Discovery, synthesis and evaluation of novel cholesterol absorption inhibitors.
  2. Pharmacokinetic Study of Oral 14C-Radiolabeled Hyzetimibe, A New Cholesterol Absorption Inhibitor.
  3. Identification of Inhibitors of Cholesterol Transport Proteins Through the Synthesis of a Diverse, S…
  4. An EZH2 blocker sensitizes histone mutated diffuse midline glioma to cholesterol metabolism inhibito…
  5. Synthesis and pharmacokinetic study of a 11C-labeled cholesterol 24-hydroxylase inhibitor using 'in-…
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Clinical Trials

Most Relevant Clinical Trials

  1. Implementation of a Pharmacy-Intervention to Enhance Prescription and Use of Lipid-Lowering Drugs
  2. Naturopathic Treatment for the Prevention of Cardiovascular Disease
  3. A Study on Possible Interactions Between Protease Inhibitors (Anti-HIV Drugs) and Drugs Which Lower …
  4. Dose-dependent Effect of Rosuvastatin on Long-term Clinical Outcomes After PCI
  5. Effects of Atorvastatin on Human Semen and Gonadal Hormones
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