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QuickView for azd5438 (compound)


Genetic Markers

Most Correlated Genes

  1. ID4
  2. XIST
  3. WIF1
  4. STEAP1
  5. CRIP1
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Pathway Enrichment

Most Correlated Biogroups

  1. regulation of nitrogen compound metabolic process
  2. organic cyclic compound binding
  3. cytosol
  4. heterocyclic compound binding
  5. cell periphery
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
  2. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
  3. L1000 CMAP - Hepatocellular carcinoma HEPG2 cells treated with small molecule perturbagens
  4. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
  5. L1000 CMAP - Prostate cancer LNCAP cells treated with small molecule perturbagens
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Literature

Most Relevant Literature

  1. AZD5438 a GSK-3a/b and CDK inhibitor is antiapoptotic modulates mitochondrial activity and protects …
  2. Cyclin-dependent kinase inhibitors AZD5438 and R547 show potential for enhancing efficacy of daunoru…
  3. AZD5438-PROTAC: A selective CDK2 degrader that protects against cisplatin- and noise-induced hearing…
  4. Restricted suitability of BODIPY for caging in biological applications based on singlet oxygen gener…
  5. Development of Second-Generation CDK2 Inhibitors for the Prevention of Cisplatin-Induced Hearing Los…
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Clinical Trials

Most Relevant Clinical Trials

  1. AZD5438 in Patients With Advanced Solid Malignancies
Explore Clinical Trials Results
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