BaseSpace
Correlation
Engine-Public
Sign In
Register
Correlation Engine 2.0
Home
My Data
Bookmarks
Collaborations
Inbox
Import Your Data
QuickView
FAQ
What is QuickView?
What can my QuickView results tell me?
What are the sources for the General Info tab in QuickView?
More QuickView FAQs
Back to top
QuickView
Curated
Studies
Body
Atlas
Disease
Atlas
Pharmaco
Atlas
Knockdown
Atlas
Genetic
Markers
Pathway
Enrichment
Literature
Clinical
Trials
0
Meta-
Analysis
QuickView
Search sequence regions
(e.g.
Heart
,
Holistic medicine
,
Aspirin
,
rs6983267
,
MDM2
,
calcium channel activity
,
Leukemia
)
Organisms
Chromosomes
Start
Stop
Homo Sapiens
Mus Musculus
Rattus Norvegicus
C. Elegans
D. Melanogaster
Saccharomyces Cerevisiae
QuickView
Go back to main search
Bookmark
Forward
QuickView
for
beta secretase
Summary
General Info
Curated Studies
Most Correlated Studies
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
Liver tissues from rats after treatment with different compounds
Brown adipose tissues of mice fed high sugar/fat diet and treated with BACE1 inhibitor RO5508887
Explore Curated Studies Results
Literature
Most Relevant Literature
BACE1 SUMOylation deregulates phosphorylation and ubiquitination in Alzheimer's disease pathology.
BACE1: More than just a β-secretase.
The Alzheimer's disease-linked protease BACE1 modulates neuronal IL-6 signaling through shedding of …
Mechanisms of amyloid-β34 generation indicate a pivotal role for BACE1 in amyloid homeostasis.
Postnatal neuronal Bace1 deletion impairs neuroblast and oligodendrocyte maturation.
Explore Literature Results
Clinical Trials
Most Relevant Clinical Trials
Phase II Trial of the Gamma-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors/Aggressive…
Study Investigating the Effects of JNJ-54861911 on Amyloid-beta Processing in Cerebrospinal Fluid (C…
A Study of Healthy Subjects to Assess the Effect of LY450139 on Amyloid Beta Peptide Production Rate…
A Safety and Tolerability Study of JNJ-54861911 in Participants With Early Alzheimer's Disease
Bridging Study of C11 Pittsburgh Compound B (PiB) and F18 Flutemetamol Brain Positron Emission Tomog…
Explore Clinical Trials Results
search
→
result
search
→
result
See more about this page
See complete FAQ