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Correlation Engine 2.0
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QuickView for caspase 11 (gene)


Body Atlas

Most Correlated Tissues

  1. Macrophage of peripheral blood
  2. Neutrophil of bone marrow
  3. Leukocyte (polymorphonuclear) of peripheral blood
  4. Natural killer cell of peripheral blood
  5. B lymphocyte (IgM memory) of spleen
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Disease Atlas

Most Correlated Diseases

  1. Meningitis
  2. Viral infections of the central nervous system
  3. Helicobacter pylori gastrointestinal tract infection
  4. Infection due to Haemophilus
  5. Infection due to Enterobacteriaceae
Explore Disease Atlas Results

Pharmaco Atlas

Most Correlated Compounds

  1. Diflunisal
  2. P2 protein, Sulfolobus
  3. alpha-naphthoflavone
  4. Vaccines, DNA
  5. monuron
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. Bcr
  2. Ikbkb
  3. Abl1
  4. LNX2
  5. MMP7
Explore Knockdown Atlas Results

Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Type 1 interferon aggravates lipopolysaccharide-induced sepsis through upregulating Caspase-11 and G…
  2. Leishmania Lipophosphoglycan Triggers Caspase-11 and the Non-canonical Activation of the NLRP3 Infla…
  3. Caspase-6 promotes activation of the caspase-11-NLRP3 inflammasome during gram-negative bacterial in…
  4. TYK2 licenses non-canonical inflammasome activation during endotoxemia.
  5. Caspase-11 counteracts mitochondrial ROS-mediated clearance of Staphylococcus aureus in macrophages.
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Clinical Trials

Most Relevant Clinical Trials

  1. Caspase Inhibition in Islet Transplantation
  2. Role of Tyrosine Kinase Lyn and Cleaved Form by Caspases in Psoriasis
  3. Analysis of the Variation in Caspase-8 Availability and Cleavage in Oral Squamous Cell Carcinoma
  4. Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma
  5. Emricasan, an Oral Caspase Inhibitor, in Subjects With NASH Cirrhosis and Severe Portal Hypertension
Explore Clinical Trials Results
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