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cdk8 protein, human
(compound)
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Genetic Markers
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Pathway Enrichment
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No biogroups found
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Curated Studies
Most Correlated Studies
Embryonic kidney HEK293 cells treated with senexin B and TNF
Colorectal cancer HCT116 wildtype or CRISPR/Cas9-mediated MED12 knock-in cells treated with IFNg
Macrophages derived from CD14+ monocytes treated with or without IFNg in the presence of LPS
Bone osteosarcoma SJSA cells with CDK19 shRNA knockdown treated with 5-fluorouracil
Colorectal cancer HCT 116 cells treated with cortistatin A
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Literature
Most Relevant Literature
Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Inhibitors of CDK8 for the Tr…
CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Media…
Cyclin-dependent kinase 8 is an independent prognosticator in uterine leiomyosarcoma.
Discovery of a novel oral type Ⅰ CDK8 inhibitor against acute myeloid leukemia.
The study of a novel CDK8 inhibitor E966-0530-45418 that inhibits prostate cancer metastasis in vitr…
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Clinical Trials
Most Relevant Clinical Trials
Phase I Study of TSN084 in Patients With Advanced Malignant Tumors.
RVU120 in Patients With Acute Myeloid Leukemia or High-risk Myelodysplastic Syndrome
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