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Correlation Engine 2.0
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(e.g. Inflammatory disorder, Intestine, Laryngoscope, Trichostatin A, rs6983267, SLC12A1)
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QuickView for kinetochore microtubule (biogroup)


Body Atlas

Most Correlated Tissues

  1. Dorsal root ganglia
  2. Fetal brain
  3. Trigeminal ganglia
  4. Vena cava
  5. Bronchus
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Disease Atlas

Most Correlated Diseases

  1. Myocardial ischemia
  2. Vesicular stomatitis Indiana virus disease
  3. Meningitis
  4. Viral infections of the central nervous system
  5. Intestinal infection due to Pseudomonas
Explore Disease Atlas Results

Pharmaco Atlas

Most Correlated Compounds

  1. TIC10
  2. trabectedin
  3. ((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide)
  4. Glial Cell Line-Derived Neurotrophic Factor
  5. PTC-209
Explore Pharmaco Atlas Results

Knockdown Atlas

Most Correlated Gene Perturbations

  1. CG4771
  2. jumu
  3. MAST4
  4. COX5A
  5. chico
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Prostate cancer LNCAP cells treated with small molecule perturbagens
  2. L1000 CMAP - Bone marrow CD34 cells treated with small molecule perturbagens
  3. The Immunological Genome Project - Immune cell lineage differentiation and maturation
  4. L1000 CMAP - Neural progenitor NPC.CAS9 cells treated with small molecule perturbagens
  5. L1000 CMAP - Breast carcinoma BT20 cells treated with small molecule perturbagens
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Literature

Most Relevant Literature

  1. Insights from an erroneous kinetochore-microtubule attachment state.
  2. Regulatory mechanisms of kinetochore-microtubule interaction in mitosis.
  3. Elevated polar ejection forces stabilize kinetochore-microtubule attachments.
  4. Structural organization of the kinetochore-microtubule interface.
  5. Increased CDK1 activity determines the timing of kinetochore-microtubule attachments in meiosis I.
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Clinical Trials

Most Relevant Clinical Trials

  1. Vinorelbine in Advanced BRAF-like Colon Cancer
  2. Phase I Dose Escalation and Expansion of Oral BAY 1143269 in Combination With Intravenous Docetaxel
  3. Phase I Study of Oral BAY 1217389 in Combination With Intravenous Paclitaxel
  4. Phase I Dose Escalation of Oral BAY1161909 in Combination With Intravenous Paclitaxel
Explore Clinical Trials Results
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