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mdm2 protein
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Curated Studies
Most Correlated Studies
Breast adenocarcinoma cells treated with nutlin-3a or/and Wip1 inhibitor GSK2830371
Hepatocyte cells of Wistar rats treated with 29 different hepatotoxic compounds
Acute monocytic leukemia MOLM-13 cells treated with the stapled peptide ALRN-6924
Neuroblastoma SHEP cells with dox-induced/uninduced MYCN before or after nutlin-3a treatment
p53-reactivating drug RITA treated HCT116 wildtype and TP53 null cells
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Literature
Most Relevant Literature
Discovery of ganoderic acid A (GAA) PROTACs as MDM2 protein degraders for the treatment of breast ca…
Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Inter…
Death-associated protein kinase 1 phosphorylates MDM2 and inhibits its protein stability and functio…
Castleman Disease with MDM2/CDK4 Protein Expression: a Potential Mimic of Inflammatory Variant of Li…
Design and linkage optimization of ursane-thalidomide-based PROTACs and identification of their targ…
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Clinical Trials
Most Relevant Clinical Trials
Phase 1 Study of the Dual MDM2/MDMX Inhibitor ALRN-6924 in Pediatric Cancer
Ascending Dose and Exploratory Expansion Study of DS-3032b, an Oral MDM2 Inhibitor, in Subjects With…
Testing the Addition of KRT-232 (AMG 232) to Usual Chemotherapy for Relapsed Multiple Myeloma
KRT-232 (AMG-232) and Decitabine in Treating Patients With Relapsed, Refractory, or Newly-Diagnosed …
A Phase Ib Study of APG-115 Single Agent or in Combination With Azacitidine or Cytarabine in Patient…
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