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protein kinase inhibitors
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Summary
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Genetic Markers
Most Correlated Genes
SERPINA3
XIST
NPR3
LCN2
CRIP1
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Pathway Enrichment
Most Correlated Biogroups
organic cyclic compound binding
heterocyclic compound binding
organic cyclic compound metabolic process
cytosol
heterocycle metabolic process
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Curated Studies
Most Correlated Studies
Gleevec treatment of BCR-ABL positive and negative leukemia cell lines
Breast cancer (ER+) combined therapy treatments associated with clinical responses
Neonatal genistein and pregnancy day 2 oviduct gene expression
Imatinib response in spleenocytes
Hematopoietic stem cells expressing the TEL-PDGFRb gene fusion with and without imatinib treatment
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Literature
Most Relevant Literature
Developing irreversible inhibitors of the protein kinase cysteinome.
PfRIO-2 kinase is a potential therapeutic target of antimalarial protein kinase inhibitors.
HPLC-DAD protein kinase inhibitor analysis in human serum.
Chemoproteomic characterization of protein kinase inhibitors using immobilized ATP.
Improved synthesis of a DNA-dependent protein kinase inhibitor IC86621.
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Clinical Trials
Most Relevant Clinical Trials
Hepatotoxicity Related to Protein Kinase Inhibitors
The Safety and Efficacy Evaluation of XSLJZ in Advanced Hepatocellular Carcinoma Patients With Multi…
Evaluation of a Promising New Combination of Protein Kinase Inhibitors on Organotypic Cultures of Hu…
HGG-TCP (High Grade Glioma - Tumor Concentrations of Protein Kinase Inhibitors)
Phase Ib Study of PI3(Phosphoinositol 3)-Kinase Inhibitor Copanlisib With MEK (Mitogen-activated Pro…
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