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simvastatin
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Summary
General Info
Genetic Markers
Most Correlated Genes
Acot1
HMGCR
EHHADH
ACOT2
NFE2
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Pathway Enrichment
Most Correlated Biogroups
organic cyclic compound metabolic process
DODD_NASOPHARYNGEAL_CARCINOMA_DN
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP
PILON_KLF1_TARGETS_DN
cytosol
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Curated Studies
Most Correlated Studies
Peripheral atherosclerosis plaques after simvastatin, losartan or pioglitazone treatment
EBV-transformed and native B-cells treated with statins
Cortical neurons exposed to excitotoxic NMDA and potentially neuroprotective compounds
Livers of rats exposed to 27 agents with different mechanisms of action for toxicity
Livers from wildtype Sprague-Dawley rats exposed to 27 chemicals
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Literature
Most Relevant Literature
Evaporative Crystallization of Simvastatin from Different Solutions Using Mid-Frequency Raman Differ…
Impact of porous microsponges in minimizing myotoxic side effects of simvastatin.
Simvastatin-Incorporated Drug Delivery Systems for Bone Regeneration.
Efficacy of simvastatin in bone regeneration after surgical removal of mandibular third molars.
Modulation of radiosensitivity of DU145 prostate carcinoma cells by simvastatin.
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Clinical Trials
Most Relevant Clinical Trials
The DDI Study of SP2086 and Simvastatin
7-day Simvastatin and Emotional Processing
Simvastatin and Emotional Processing (OxSTEP)
Sarilumab Effect on the Pharmacokinetics of Simvastatin
Simvastatin in Chronic Obstructive Pulmonary Disease (COPD)
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