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thiostrepton
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Summary
General Info
Genetic Markers
Most Correlated Genes
HSPA6
HSPA1B
HMOX1
KRCC1
HSPA1A
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Pathway Enrichment
Most Correlated Biogroups
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
PODAR_RESPONSE_TO_ADAPHOSTIN_UP
CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN
NUYTTEN_EZH2_TARGETS_DN
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Curated Studies
Most Correlated Studies
Prostate cancer PC3 and LNCaP cells treated with siomycin A
Breast adenocarcinoma MCF-7 cells treated with thiostrepton
Glioma stem cell treated with MELK-signaling inhibitors
Nasopharyngeal carcinoma cells from patient biopsies treated with natural antibiotic thiostrepton
Broad Connectivity Map (CMAP 2.0) compound database
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Literature
Most Relevant Literature
The bacterial thiopeptide thiostrepton. An update of its mode of action, pharmacological properties …
Development of a thiostrepton-free system for stable production of PLD in Streptomyces lividans SBT5…
Autophagy induction by thiostrepton for the improvement of anticancer therapy.
Thiostrepton induces ferroptosis in pancreatic cancer cells through STAT3/GPX4 signalling.
Cobalt(III)-Catalyzed C-H Amidation of Dehydroalanine for the Site-Selective Structural Diversificat…
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Clinical Trials
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Study of RSO-021 in Patients With Malignant Pleural Effusion Due to Advanced/Metastatic Solid Tumors…
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