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QuickView for xpo1 protein


Curated Studies

Most Correlated Studies

  1. Mantle cell lymphoma JVM-2 cells with TP53 shRNA knockdown and treated with KPT-185
  2. Lung cancer A549 cells infected for 1hr with respiratory syncytial virus strain A2
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Literature

Most Relevant Literature

  1. Safety of selinexor as the only exportin 1 (XPO1) inhibitor so far: a post-marketing study based on …
  2. Exportin 1-mediated nuclear/cytoplasmic trafficking controls drug sensitivity of classical Hodgkin's…
  3. C646 degrades Exportin-1 to modulate p300 chromatin occupancy and function.
  4. Differential impact of exportin-1-mediated nuclear export of RNAs on the RNA content of extracellula…
  5. Exportin 1 governs the immunosuppressive functions of myeloid-derived suppressor cells in tumors thr…
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Clinical Trials

Most Relevant Clinical Trials

  1. A Phase 1 Trial of a Novel XPO1 Inhibitor in Patients With Advanced Solid Tumors
  2. Selinexor and Pembrolizumab for the Treatment of Cisplatin-Ineligible or Cisplatin-Refractory Locall…
  3. Selinexor for the Treatment of Intermediate and High-Risk Smoldering Multiple Myeloma
  4. A Study of Different Dosing Schedules of Selinexor in Sarcoma Patients
  5. Selinexor, Pomalidomide, and Dexamethasone With or Without Carfilzomib for the Treatment of Patients…
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