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regulation of necroptotic process
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Summary
General Info
Body Atlas
Most Correlated Tissues
Pituitary gland
Heart ventricle
Lung
Stomach fundus
Fetal brain
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Disease Atlas
Most Correlated Diseases
Disease due to Enterovirus
Listeriosis
Vesicular stomatitis Indiana virus disease
Infection due to Enterobacteriaceae
Toxoplasmosis
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Pharmaco Atlas
Most Correlated Compounds
CP 724714
Floxuridine
Carrageenan
GSK690693
ARQ 197
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Knockdown Atlas
Most Correlated Gene Perturbations
SLC4A11
PCDH11X
CHMP2A
IRF7
TBC1D23
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Curated Studies
Most Correlated Studies
Mouse embryonic stem cells depleted of Klf2, Klf4, and Klf5 by ectopic expression of shRNA
L1000 CMAP - Neural progenitor NPC.CAS9 cells treated with small molecule perturbagens
Hepatoma HuH-7 cells treated with IFN-α, IFN-ß, IFN-λ1, IFN-λ2, or IFN-λ3
Dermal fibroblasts from STAT2 deficient patient cultured with IFNa
L1000 CMAP - Neuronal NEU cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
The AMPK-Parkin axis negatively regulates necroptosis and tumorigenesis by inhibiting the necrosome.
RIP3/MLKL regulates necroptosis via activating 4EBP1-eIF4E pathway.
Ppm1b negatively regulates necroptosis through dephosphorylating Rip3.
The circRNA CNEACR regulates necroptosis of cardiomyocytes through Foxa2 suppression.
Inhibition of inflammatory factor TNF-α by ferrostatin-1 in microglia regulates necroptosis of oligo…
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There were no clinical trials for regulation of necroptotic process
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