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1-phosphatidylinositol-3-kinase activity
(biogroup)
Summary
General Info
Body Atlas
Most Correlated Tissues
Corpus callosum
Medulla
Ventral tegmental area
Medulla oblongata
Midbrain
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Disease Atlas
Most Correlated Diseases
Pyloric ulcer
Alpha-1-antitrypsin deficiency
Dermatosis due to mites
Poisoning by drug AND/OR medicinal substance
Disorder of digestive system
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Pharmaco Atlas
Most Correlated Compounds
Glesatinib
CGP 60474
A 443654
AZD1480
GSK-1059615
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Knockdown Atlas
Most Correlated Gene Perturbations
CCDC170
PPP2R2C
NCL
TLK2
MTTP
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Curated Studies
Most Correlated Studies
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Breast carcinoma BT20 cells treated with small molecule perturbagens
PBMC microRNA expression from pulmonary tuberculosis and sarcoidosis patients
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
L1000 CMAP - Breast adenocarcinoma SKBR3 cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
The beta3-adrenergic agonist CL316,243 inhibits insulin signaling but not glucose uptake in primary …
Interleukin-6 directly increases glucose metabolism in resting human skeletal muscle.
Identification of pathways controlling muscle protein metabolism in uremia and other catabolic condi…
Muscle glycogen inharmoniously regulates glycogen synthase activity, glucose uptake, and proximal in…
Therapeutic actions of an insulin receptor activator and a novel peroxisome proliferator-activated r…
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Clinical Trials
Most Relevant Clinical Trials
Phosphatidylinositol 3-kinase (PI3K) Alpha iNhibition In Advanced Breast Cancer
Rapamycin Treatment for Activated Phosphoinositide 3-Kinase δ Syndrome
Phase 1 Study of PI3 (Phosphatidylinositol-3)-Kinase Inhibitor Copanlisib With Gemcitabine or Cispla…
Study of Phosphatidylinositol-3-kinase (PI3K) Inhibitor Idelalisib (GS-1101) in Waldenström Macroglo…
Defective Atypical Protein Kinase C (PKC) Activation in Diabetes and Metabolic Syndrome
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