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rs6983267
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DNMT1
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calcium channel activity
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DNA-methyltransferase activity
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Summary
General Info
Body Atlas
Most Correlated Tissues
Endometrium
Hematopoietic stem cell of bone marrow
Hippocampus
Thalamus
Globus pallidus
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Disease Atlas
Most Correlated Diseases
Centromeric instability of chromosomes 1,9 and 16 and immunodeficiency
Systemic inflammatory response syndrome
Shock
Sensorineural hearing loss
Cryptosporidiosis
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Pharmaco Atlas
Most Correlated Compounds
valrubicin
Endothelin-1
niguldipine
PCI 24781
I-BET 151
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Knockdown Atlas
Most Correlated Gene Perturbations
491333
RIOK2
UBE4A
NRF1
Mir92-1
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Curated Studies
Most Correlated Studies
Embryonic stem cells with DNMT1, DNMT3a and DNMT3b triple knockout and NRF1 siRNA knockdown
Mouse Phenotypes - Disorder of immune structure
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
Induction of pluripotency in mouse somatic cells with novel factors
L1000 CMAP - Skeletal muscle SKL.C cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
Reduction of pancreatic cancer cell viability and induction of apoptosis mediated by siRNA targeting…
Electrochemical immunosensing platform for DNA methyltransferase activity analysis and inhibitor scr…
An electrochemical assay for DNA methylation, methyltransferase activity and inhibitor screening bas…
Ultrasensitive electrochemical immunoassay for DNA methyltransferase activity and inhibitor screenin…
Direct and continuous fluorescence-based measurements of Pyrococcus horikoshii DNA N-6 adenine methy…
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Clinical Trials
Most Relevant Clinical Trials
Analysis of DNA Methylation in Spondyloarthritis
MGMT-NET: O6-methylguanine-DNA Methyltransferase (MGMT) Status in Neuroendocrine Tumors: Predictive …
Impact of O6-methylguanine-DNA Methyltransferase (MGMT) Promoter Methylation and MGMT Expression on …
The Influence of Thiopurine Methyltransferase Activity on Toxicity After High-dose Methotrexate in C…
Effect of DNMT SNPs on DNA Methylation in Primary ITP
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