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alpha-tubulin binding
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Summary
General Info
Body Atlas
Most Correlated Tissues
Vestibular nuclei superior
Midbrain
Subthalamic nucleus
Frontal cortex
Colon
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Disease Atlas
Most Correlated Diseases
Vesicular stomatitis Indiana virus disease
Pyloric ulcer
Perforation of tympanic membrane
Chronic sinusitis
Injury of external ear
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Pharmaco Atlas
Most Correlated Compounds
JM 3100
GSK-1059615
WYE 125132
NVP-AEW541
Apitolisib
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Knockdown Atlas
Most Correlated Gene Perturbations
ZNF300
DIDO1
NOP2
NR5A1
NCL
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Curated Studies
Most Correlated Studies
Tumor formation by ATG5 KO cells
Kidneys from male C57BL6 mice 28 days after left proximal ureter ligations
Carotid arteries from atherogenic ApoE knockout mice with carotid artery injury
Glomerulonephrotic and healthy tissue from C57BL6.MRLc1 congenic mice
Neural development of iPSCs derived from Autistic patients with BCKD-kinase mutations
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Literature
Most Relevant Literature
Factors affecting solubilization of a poorly soluble novel tubulin-binding agent.
Tubulin binds to the cytoplasmic loop of TRESK background K⁺ channel in vitro.
A tubulin binding peptide targets glioma cells disrupting their microtubules, blocking migration, an…
ABT-751, a novel tubulin-binding agent, decreases tumor perfusion and disrupts tumor vasculature.
Structural basis of protein condensation on microtubules underlying branching microtubule nucleation…
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Clinical Trials
Most Relevant Clinical Trials
Phase I Dose Finding Study of SSR97225 Given in Patients With Refractory Cancer
Study of TPI 287 Administered Every 21 Days in Patients With Advanced Malignancies
A Study of CCI-001 in Patients With Recurrent and/or Metastatic Solid Tumours
Study of TPI 287 in Patients With Advanced Malignancies
COlchicine for the Prevention of Post Electrical Cardioversion Recurrence of AF
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