Correlation Engine 2.0
Clear Search sequence regions


Adoptive cell therapy using tumor-infiltrating lymphocytes (TIL) is arguably the most effective treatment for patients with metastatic melanoma. With higher response rates than ipilimumab or IL-2, and longer durations of response than vemurafenib, TIL therapy carries the potential to transform current outcomes in melanoma, while also defining the way cell-based immunotherapy gets incorporated into mainstream cancer treatment. This paper will review the current state of TIL therapy in melanoma, the strategies to improve its efficacy, the current obstacles, and future directions to expand the availability of TIL to the general patient population.

Citation

Sylvia Lee, Kim Margolin. Tumor-infiltrating lymphocytes in melanoma. Current oncology reports. 2012 Oct;14(5):468-74

Expand section icon Mesh Tags

Expand section icon Substances


PMID: 22878966

View Full Text