QuickView for Allopurinol (compound)

Urbol; Uriprim; AIDS-068904; Aloral; Alositol; Lopurin; Embarin; 4-Hydroxypyrazolo(3,4-d)pyrimidine; 1H-Pyrazolo[3, 4-d]pyrimidin-4-ol; KBioGR_000550.
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Urbol; Uriprim; AIDS-068904; Aloral; Alositol; Lopurin; Embarin; 4-Hydroxypyrazolo(3,4-d)pyrimidine; 1H-Pyrazolo[3, 4-d]pyrimidin-4-ol; KBioGR_000550; NSC 1390; 39464-14-7; 1H-Pyrazolo[3,4-d]pyrimidin-4-ol, monosodium salt; Aluline; Apurin; 4-Hydroxypyrazolo[3,4-d]pyrimidine; Sodium allopurinol; Ketobun-A; 22767-92-6; 1H-Pyrazolo[3,4-d]pyrimidin-4-ol; BW 56158; 4(3H)-pyrimidinone, 2-methyl-; Allopurinol [USAN:BAN:INN:JAN]; 17795-21-0; 1,5-Dihydro-4H-pyrazolo(3,4-d)pyrimidin-4-one; 1,5-Dihydro-4H-pyrazolo(3,4-d)pyrimidine-4-one; Urtias; Milurit; NSC-1390; Spectrum4_000135; Dabroson; DRG-0056; SPBio_000056; Spectrum2_000098; Riball; Allopurinol, sodium deriv.; InChI=1/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10; NCGC00015094-01; Zyloric; 1,5-Dihydro-4H-pyrazolo(3,4-d)pyrimidin-4-one (9CI); MLS000069453; 4-Hydroxypyrazolo[3, 4-d]pyrimidine; Apurol; HPP; Urtias 100; 4'-Hydroxypyrazolol[3,4-d]pyrimidine; Gichtex; KBio2_002954; Spectrum_000026; 4-Hydroxy-1H-pyrazolo(3,4-d)pyrimidine; Ketanrift; Progout; AIDS027531; Prestwick_511; NSC1390; NINDS_000685; Epidropal; NCGC00091134-01; ZINC05177572; Zyloprim; Allural; AL-100; Ailural; NCIOpen2_001825; Allo-Puren; Cosuric; 184856-42-6; Allopurinol (I); 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro-, monosodium salt; Alopurinol [INN-Spanish]; Xanturat; Foligan; Spectrum3_000289; KBio2_000386; nchembio732-comp4; AIDS-045549; Ailurial; Urolit; Urobenyl; 4H-Pyrazolo(3,4-d)pyrimidin-4-one; 4-Hydroxypyrazolyl[3,4-d]pyrimidine; Lopac-A-8003; Anoprolin; Atisuril; Dura Al; DivK1c_000685; Allopurinol sodium salt; Uripurinol; Miniplanor; KBio2_005522; 4-Hydroxy-3,4-pyrazolopyrimidine; 4H-Pyrazolo[3, 4-d]pyrimidin-4-one, 1,5-dihydro-; 4-Hydroxy-1H-pyrazolo[3, 4-d]pyrimidine; Suspendol; Allozym; Remid; Monarch; 4-Hydroxypyrazolyl(3,4-d)pyrimidine; Allopurinolum [INN-Latin]; Apulonga; ZINC00000896; 1,5-Dihydro-pyrazolo[3,4-d]pyrimidin-4-one; NSC101655; Adenock; Hexanuret; Gotax; CCRIS 626; Urosin; SMR000059083; Ledopur; 315-30-0; 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro-; 1H-Pyrazolo(3,4-d)pyrimidin-4-ol; 4H-pyrazolo[3,4-d]pyrimidin-4-one, 1,7-dihydro-; 4H-Pyrazolo(3,4-d)pyrimidin-4-one, 1,5-dihydro-; Bloxanth; Allopurinol(I); 4-Hydroxypyrazolopyrimidine; AIDS068904; NSC108836; Allopur; AIDS045549; 4-HPP; Epuric; 4-Hydroxypyrazolyl[3, 4-d]pyrimidine; Takanarumin; BW 56-158; Caplenal; Allopurinol; EU-0100102; B. W. 56-158; 2-methylpyrimidin-4(3H)-one; 1, 5-Dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; Bleminol; EINECS 206-250-9; Anzief; Geapur; Nektrohan; 4-Hydroxy-1H-pyrazolo[3,4-d]pyrimidine; KBio1_000685; KBio3_001298; 4'-Hydroxypyrazolol(3,4-d)pyrimidine; Dabrosin; Cellidrin; AIDS-027531; KBioSS_000386; NSC 101655; Uricemil; HSDB 3004; Lysuron; Hamarin
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Allopurinol Sodium; Allopurinolum [INN-Latin]; Alopurinol [INN-Spanish]

Allopurinol and its active metabolite, oxypurinol, inhibits the enzyme xanthine oxidase, blocking the conversion of the oxypurines hypoxanthine and xanthine to uric acid. Elevated concentrations of oxypurine and oxypurine inhibition of xanthine oxidase through negative feedback results in a decrease in the concentrations of uric acid in the serum a...
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Allopurinol and its active metabolite, oxypurinol, inhibits the enzyme xanthine oxidase, blocking the conversion of the oxypurines hypoxanthine and xanthine to uric acid. Elevated concentrations of oxypurine and oxypurine inhibition of xanthine oxidase through negative feedback results in a decrease in the concentrations of uric acid in the serum and urine. Allopurinol also facilitates the incorporation of hypoxanthine and xanthine into DNA and RNA, leading to a feedback inhibition of de novo purin synthesis and a decrease in serum uric acid concentrations as a result of an increase in nucleotide concentration.
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