QuickView for CEBPb (gene)

Gene Symbol:

CEBPB Homo sapiens

Full name:

CCAAT/enhancer binding protein beta

Synonyms:

C/EBP-beta, IL6DBP, NF-IL6, TCF5, CCAAT/enhancer-binding protein beta, CCAAT/enhancer binding protein (C/EBP), beta, interleukin 6-dependent DNA-binding protein, nuclear factor NF-IL6, nuclear factor of interleukin 6, transcription factor 5, transcription factor C/EBP beta

Genomic Location:

Chr 20: 48240783-48242619

Description:

This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory respons...

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This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with distinct biological functions.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GTATTAT_MIR3693P ,  TTANTCA_UNKNOWN ,  SREBP1_02 ,  TTGCWCAAY_CEBPB_02 ,  MYCMAX_03 ,  YTATTTTNR_MEF2_02 ,  CACGTG_MYC_Q2 ,  TTCCGTT_MIR191 ,  CCTGAGT_MIR510 ,  VDR_Q6 ,  WGTTNNNNNAAA_UNKNOWN ,  SREBP1_Q6 ,  MYB_Q5_01 ,  GATA1_04 ,  TGACCTY_ERR1_Q2 ,  CREBP1_Q2 ,  TATAAA_TATA_01 ,  AGCATTA_MIR155 ,  LFA1_Q6 ,  GGGCGGR_SP1_Q6 ,  CTTTAAR_UNKNOWN ,  RNGTGGGC_UNKNOWN ,  TCTATGA_MIR376A_MIR376B ,  NMYC_01 ,  CHOP_01 ,  CEBP_C ,  GATA1_05 ,  SREBP_Q3 ,  TGACAGNY_MEIS1_01 ,  ER_Q6_02 ,  TGACATY_UNKNOWN ,  TATTATA_MIR374 ,  CP2_01 ,  TAXCREB_01 ,  MYB_Q3

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-191 ,  Predicted Gene Targets for miR-369-3p ,  Predicted Gene Targets for miR-376 ,  Predicted Gene Targets for miR-155 ,  Predicted Gene Targets for miR-374

Cytogenetic Map:

20q13.13

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