QuickView for DLX5;jsessionid=6792FF91CAB4DC92C8757C78E7EA9F53 (gene)

Gene Symbol:

DLX5 Homo sapiens

Full name:

distal-less homeobox 5

Synonyms:

SHFM1D, homeobox protein DLX-5, distal-less homeo box 5, split hand/foot malformation type 1 with sensorineural hearing loss

Genomic Location:

Chr 7: 96487638-96492079

Description:

This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7, may be associa...

View Full Description

This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7, may be associated with split-hand/split-foot malformation.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RYTTCCTG_ETS2_B ,  P53_DECAMER_Q2 ,  RSRFC4_01 ,  AML_Q6 ,  HEN1_01 ,  CIZ_01 ,  ARP1_01 ,  STAT6_01 ,  CTTTGA_LEF1_Q2 ,  COUP_01 ,  COMP1_01 ,  CATTTCA_MIR203 ,  CATGTAA_MIR496 ,  RP58_01 ,  CDPCR3_01 ,  STAT5A_03 ,  NKX25_02 ,  GTGCCTT_MIR506 ,  HLF_01 ,  TCTATGA_MIR376A_MIR376B ,  HAND1E47_01 ,  MSX1_01 ,  TEF_Q6 ,  ZF5_B ,  FOXM1_01 ,  TAXCREB_01

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-376 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-203 ,  Predicted Gene Targets for miR-496 ,  Predicted Gene Targets for miR-543

Cytogenetic Map:

7q21.3

search → result