QuickView for Dezocine (compound)

57236-36-9; Dezocine monohydrobromide; UM 972; WY 16225; 5,11-Methanobenzocyclodecen-3-ol, 5,6,7,8,9,10,11,12-octahydro-13-amino-5-methyl-, hydrobromide, (5R-(5-alpha,11-alpha,13S*))-; NIH 8834; MCV 4206; Dezocine hydrobromide

Dezocina [INN-Spanish]; Dezocinum [INN-Latin]

Dezocine is a opioid analgesic drug of mixed agonist-antagonist type. It binds with stereospecific receptors at many sites within the central nervous system (CNS) to alter processes affecting both the perception of pain and the emotional response to pain. At least 2 of these types of receptors (mu and kappa) mediate analgesia. Mu receptors are wide...
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Dezocine is a opioid analgesic drug of mixed agonist-antagonist type. It binds with stereospecific receptors at many sites within the central nervous system (CNS) to alter processes affecting both the perception of pain and the emotional response to pain. At least 2 of these types of receptors (mu and kappa) mediate analgesia. Mu receptors are widely distributed throughout the CNS, especially in the limbic system (frontal cortex, temporal cortex, amygdala, and hippocampus), thalamus, striatum, hypothalamus, and midbrain as well as laminae I, II, IV, and V of the dorsal horn in the spinal cord. Kappa receptors are localized primarily in the spinal cord and in the cerebral cortex.
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