QuickView for Gli1 (gene)

Gene Symbol:

GLI1 Homo sapiens

Full name:

GLI family zinc finger 1

Synonyms:

GLI, zinc finger protein GLI1, GLI-Kruppel family member GLI1, glioma-associated oncogene 1, glioma-associated oncogene homolog 1 (zinc finger protein), oncogene GLI

Genomic Location:

Chr 12: 56140201-56152312

Description:

This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants enco...

View Full Description

This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

SP1_01 ,  GATA1_03 ,  CREBP1CJUN_01 ,  ZIC1_01 ,  VDR_Q6 ,  ARP1_01 ,  ZIC3_01 ,  TTF1_Q6 ,  TGACCTY_ERR1_Q2 ,  GGGAGGRR_MAZ_Q6 ,  TGAYRTCA_ATF3_Q6 ,  CREBP1_Q2 ,  GTGACGY_E4F1_Q6 ,  CAGGTG_E12_Q6 ,  E47_02 ,  CREB_02 ,  GGGCGGR_SP1_Q6 ,  CCCNNGGGAR_OLF1_01 ,  SP1_Q6 ,  MEIS1_01 ,  KCCGNSWTTT_UNKNOWN ,  RORA1_01 ,  AREB6_03 ,  RNGTGGGC_UNKNOWN ,  MTF1_Q4 ,  TTGTTT_FOXO4_01 ,  ATF1_Q6 ,  ARGGGTTAA_UNKNOWN ,  ZIC2_01 ,  CTGCAGY_UNKNOWN ,  TGACGTCA_ATF3_Q6 ,  TGACAGNY_MEIS1_01 ,  CTTTGT_LEF1_Q2 ,  ER_Q6_01 ,  LXR_Q3 ,  DR4_Q2 ,  CREB_01 ,  CP2_01 ,  SP1_Q2_01

View More

View Less

Cytogenetic Map:

12q13.3

search → result