QuickView for Hoxb7 (gene)

Gene Symbol:

HOXB7 Homo sapiens

Full name:

homeobox B7

Synonyms:

HHO.C1, HOX2, HOX2C, Hox-2.3, homeobox protein Hox-B7, homeo box 2C, homeo box B7, homeo box c1 protein, homeobox protein HHO.C1, homeobox protein Hox-2C

Genomic Location:

Chr 17: 44039593-44043382

Description:

This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of th...

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This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Danio rerio ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  E12_Q6 ,  IRF1_01 ,  PAX4_04 ,  MAZR_01 ,  CEBPA_01 ,  DR3_Q4 ,  MYOD_01 ,  USF_Q6 ,  ARNT_01 ,  VDR_Q3 ,  HOXA4_Q2 ,  AP3_Q6 ,  MYCMAX_03 ,  CACGTG_MYC_Q2 ,  NGFIC_01 ,  MAX_01 ,  CIZ_01 ,  EVI1_04 ,  CEBP_Q2_01 ,  YATTNATC_UNKNOWN ,  HP1SITEFACTOR_Q6 ,  XBP1_01 ,  WGTTNNNNNAAA_UNKNOWN ,  MEIS1BHOXA9_01 ,  FAC1_01 ,  CTTTGA_LEF1_Q2 ,  GR_Q6_01 ,  NKX22_01 ,  CTAWWWATA_RSRFC4_Q2 ,  GATA1_04 ,  TCF4_Q5 ,  CTTTGTA_MIR524 ,  GGGAGGRR_MAZ_Q6 ,  MYCMAX_02 ,  CEBP_Q2 ,  SOX9_B1 ,  LEF1_Q6 ,  CDP_02 ,  SREBP1_01 ,  YYCATTCAWW_UNKNOWN ,  CAGGTG_E12_Q6 ,  SP1_Q4_01 ,  GR_Q6 ,  HNF4_Q6 ,  EVI1_05 ,  ACTACCT_MIR196A_MIR196B ,  MYCMAX_01 ,  GGGCGGR_SP1_Q6 ,  S8_01 ,  CTTTAAR_UNKNOWN ,  E47_01 ,  SP1_Q6 ,  HFH8_01 ,  USF_01 ,  PAX8_B ,  RNGTGGGC_UNKNOWN ,  MEIS1AHOXA9_01 ,  NMYC_01 ,  CHX10_01 ,  USF_Q6_01 ,  TAATTA_CHX10_01 ,  TTGTTT_FOXO4_01 ,  GR_01 ,  YTAAYNGCT_UNKNOWN ,  CHOP_01 ,  CEBP_C ,  CART1_01 ,  MSX1_01 ,  GATA1_05 ,  MEF2_03 ,  TGATTTRY_GFI1_01 ,  ICSBP_Q6 ,  CTTTGT_LEF1_Q2 ,  ER_Q6_01 ,  CDC5_01 ,  AACTTT_UNKNOWN ,  MZF1_02 ,  ACAWYAAAG_UNKNOWN ,  USF_02 ,  TCF1P_Q6 ,  SP1_Q2_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-196 ,  Predicted Gene Targets for miR-376c

Cytogenetic Map:

17q21.32

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